Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
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EC number: 943-224-2 | CAS number: -
Endpoint summary
Administrative data
Link to relevant study record(s)
Description of key information
No data are available; a theoretical assessment of the toxicokinetic properties of the substance is performed. |
Key value for chemical safety assessment
- Bioaccumulation potential:
- no bioaccumulation potential
Additional information
The substance is a toxicologically and chemically inert, refractory inorganic solid. The substance is insoluble in water. Based on the physicochemical properties of the read across substance, absorption is not predicted following oral, dermal or inhalation exposure. This is supported by the absence of toxicity in an acute oral toxicity study at the limit dose of 2000 mg/kg bw and by the absence of toxicity in a 28-day rat study at the limit dose of 1000 mg/kg bw/d. The substance is not a skin irritant; mild transient effects seen in an eye irritation study are consistent with mechanical rather than chemical irritation. The substance is not a skin sensitiser and is not mutagenic in vitro. In the absence of oral absorption, ingested material will be excreted quantitatively and unchanged in the feces. Depending on the particle size, inhaled material may be retained in the lung, but is not predicted to be systemically absorbed. |
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
