Registration Dossier
Registration Dossier
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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
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EC number: 222-590-0 | CAS number: 3544-94-3
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Administrative data
First-aid measures
Description of first aid
General advice
After inhalation: Take the victim abroad.
After skin contact: In case of skin contact, wash with plenty of water. Remove contaminated clothing.
After eye contact: In case of contact with the eyes, clean for 15 minutes with plenty of water separating the Eyelids
After ingestion: Induce vomiting. Rinse the mouth with water.
Fire-fighting measures
Suitable extinguishing media: water spray, powder, foam.
Recommendations for firefighting personnel: Wear appropriate breathing equipment and protective clothing.
Accidental release measures
Methods and material for containment and cleaning after spill / leak / gas leak:
Carefully collect the substance, store in closed containers for destruction.
Dispose of waste in accordance with applicable regulations and regulations.
Handling and storage
Written confirmation of application of Strictly Controlled Conditions has been received from every affected Distributor and Downstream Processor/User of the Registrant’s intermediate.
Precautions for safe handling
Protective Measures
Avoid contact with eyes, skin or clothing. Wear appropriate protective equipment. Avoid breathing the dust In case of insufficient ventilation, use respiratory protection.
Conditions for safe storage, including possible incompatibilities
Keep in airtight containers. Protect them from moisture and excessive heat.
Specific end uses: Intermediate substance. Formulation of medications.
Transport information
Land transport (UN RTDG/ADR/RID)
- UN number:
- Transport is not dangerous
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Inland waterway transport (UN RTDG/ADN(R))
- UN number:
- Transport is not dangerous
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Marine transport (UN RTDG/IMDG)
- UN number:
- Transport is not dangerous
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Air transport (UN RTDG/ICAO/IATA)
- UN number:
- Transport is not dangerous
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Exposure controls / personal protection
Written confirmation of application of Strictly Controlled Conditions has been received from every affected Distributor and Downstream Processor/User of the Registrant’s intermediate.
Exposure controls: Work in well-ventilated areas. Avoid contact with skin and eyes. Avoid ingestion and inhalation.
Individual protection measures, such as personal protective equipment
Eye protection: Safety glasses or face shield.
Skin protection: The use of protective gloves is recommended.
Respiratory protection: Use approved respirators
Stability and reactivity
Chemical stability: Under normal conditions of use and storage, the chloramphenicol hemisuccinate acid is stable.
Avoid excessive heat.
Hazardous decomposition products: Toxic fumes of: carbon dioxide, nitrogen oxide.
Disposal considerations
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.