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EC number: - | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Boiling point
Administrative data
Link to relevant study record(s)
- Endpoint:
- boiling point
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- from 2018-03-16 to 2018-05-24
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Reason / purpose for cross-reference:
- reference to same study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 103 (Boiling Point)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.2 (Boiling Temperature)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EPA OPPTS 830.7220 (Boiling Point / Boiling Range)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- differential scanning calorimetry
- Remarks:
- DSC results confirmed by capillary method
- Key result
- Boiling pt.:
- >= 100.1 - <= 101.3 °C
- Atm. press.:
- 1 013.25 hPa
- Decomposition:
- yes
- Conclusions:
- The boiling range of the test item under decomposition was determined to be 100.1 to 101.3 °C at 1013 hPa.
- Executive summary:
A study was conducted according to OECD test guideline 103, Regulation (EC) No 440/2008 method A.2 and EPA OCSPP test guideline 830.7220 to determine the boiling point of the test item using differential scanning calorimetry. The test item was weighed out into an aluminium crucible under an inert atmosphere (nitrogen). Three tests were performed. As reference crucible, an empty aluminium crucible was used. When heating up during DSC measurement three endothermic and one exothermic effect were observed and the boiling point of the test item could not clearly be assigned. Thus, the results of the DSC method were confirmed by a test in a test cube and the measurement with the capillary method. Finally and after correction of the temperatures to normal pressure the boiling range of the test item under decomposition was determined to be 100.1 °C to 101.3 °C (lowest and highest onset temperature) at 1013 hPa.
Reference
In the temperature range of 50 – 140 °C a further endothermic effect occurred (after determination of the melting point). Between 240 and 290 °C one or two small endothermic effects, respectively, as well as one small exothermic could be detected.
Table 1: Results of DSC measurement
No. |
Sample weight (mg) |
Onset of effect (°C) |
Range of effect (°C) |
Atmospheric pressure (hPa) |
PN15220 |
9.26 |
99.30 |
50 – 130 (endo) |
988.7 |
PN15221 |
16.33 |
100.52 |
70 – 130 (endo) |
988.7 |
PN15248 |
10.17 |
101.40 |
60 – 140 (endo) |
1015.2 |
During the heating phase three small endothermic effects were observed, which can’t be clearly assigned to a melting of the test item. Thus, the capillary method as well as a test in a test tube were performed for a verification of the DSC measurements.
The test item was filled in a test tube and heated up by means of a lighter. It showed the start of boiling at 86.4 °C. At this temperature, the test item got dark coloured.
For the capillary method, two capillaries were filled with the test item up to a height of 9 mm. The capillaries were heated up from 90 to 130 °C with a constant heating rate of 1 K/min in the BÜCHI melting point apparatus. The test item was visually observed while increasing the temperature. The boiling of the test item could be observed at 99.1 and 99.0 °C at a pressure of 991 hPa.
The endothermic effect in the DSC in the temperature range of 50 to 140 °C was determined as boiling point of the test item under decomposition. For the correction of the boiling temperature to normal pressure the test item was assigned to chemical group 3 (e.g. Ester). According to appendix 8.1 a correction value φ = 4.95 was used for a temperature of 90 – 100 °C. The lowest measured onset temperature corrected to the normal pressure was 100.10 °C and the highest onset temperature was 101.34 °C. The corrected boiling point temperatures differed more than 0.5 °C from the mean value of 100.92 °C. The boiling range of the test item under decomposition was determined to be 100 to 101 °C at 1013 hPa.
Description of key information
The boiling range of the test item under decomposition was determined to be 100.1 to 101.3 °C at 1013 hPa.
Key value for chemical safety assessment
Additional information
A study was conducted according to OECD test guideline 103, Regulation (EC) No 440/2008 method A.2 and EPA OCSPP test guideline 830.7220 to determine the boiling point of the test item using differential scanning calorimetry. The test item was weighed out into an aluminium crucible under an inert atmosphere (nitrogen). Three tests were performed. As reference crucible, an empty aluminium crucible was used. When heating up during DSC measurement three endothermic and one exothermic effect were observed and the boiling point of the test item could not clearly be assigned. Thus, the results of the DSC method were confirmed by a test in a test cube and the measurement with the capillary method. Finally and after correction of the temperatures to normal pressure the boiling range of the test item under decomposition was determined to be 100.1 °C to 101.3 °C (lowest and highest onset temperature) at 1013 hPa.
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