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EC number: 227-774-4 | CAS number: 5977-14-0
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
- Endpoint:
- biodegradation in water: screening test, other
- Remarks:
- Test wa performed acc to DIN 38412 part 25, similar to OECD 302 B; no GLP
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 17 May 1989 - 14 June 1989
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- test procedure in accordance with national standard methods with acceptable restrictions
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- OECD Guideline 302 B (Inherent biodegradability: Zahn-Wellens/EMPA Test)
- Deviations:
- yes
- Remarks:
- origins of the sludge and test substance concentration
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- EU Method C.9 (Biodegradation: Zahn-Wellens Test)
- Deviations:
- yes
- Remarks:
- already mentioned
- Principles of method if other than guideline:
- DIN 38 412 Part 25 (1984). This method is corresponding with small differences to the Guideline OECD 302B and EU Test method C.9.
- GLP compliance:
- no
- Remarks:
- newly generated from 1989 report
- Specific details on test material used for the study:
- Test substance dissolved in approx. 30% in aqueous solution
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- sewage, industrial, non-adapted
- Details on inoculum:
- Mixture of activated sludge from the sewage treatment plant from one industrial site and activated sludge from the other industrial site.
- Duration of test (contact time):
- 28 d
- Initial conc.:
- 357.9 mg/L
- Based on:
- test mat.
- Parameter followed for biodegradation estimation:
- DOC removal
- Details on study design:
- Stock solution:
5 g 30% acetoacetamide solution were mixed with 1800 ml de-ionized water, the pH adjusted from 6.9 to 7.1. This batch was stirred over a period of 24 hours at 22°C. The resulting clear solution was filled up with de-ionized water to a final volume of 2000 ml and used as stock solution.
Inoculum:
Washing the sediment from the activated sludge two times by centrifuging and resuspending in mineral medium. 12 g/L (=1240 mg dry mass/L) was used for the batch.12 g/L of wet centrifuged sludge was used as inoculum.
241 ml/L stock solution was added. Test item concentration: 357.9 mg/L - Reference substance:
- diethylene glycol
- Remarks:
- 271.6 mg DOC/L
- Test performance:
- During the first 7 days of the test the DOC exhaustion achieved >70% of the carbon content of the added test substance, but during the following 7 days the rate of degradation stayed at the plateau in the range of 70% to 72%.
- Parameter:
- % degradation (DOC removal)
- Value:
- 32
- Sampling time:
- 1 d
- Parameter:
- % degradation (DOC removal)
- Value:
- 70
- Sampling time:
- 9 d
- Parameter:
- % degradation (DOC removal)
- Value:
- 68
- Sampling time:
- 21 d
- Key result
- Parameter:
- % degradation (DOC removal)
- Value:
- 64
- Sampling time:
- 28 d
- Remarks on result:
- other: inherently biodegradable
- Details on results:
- The results were confirmed by additionally conducted COD control analyses. The analysis of the COD before adding the inoculum resulted in a start value of 510 mg/L COD from the test substance in the test batch. The final COD (28 days, test minus blank) was 160 mg/L, corresponding to 69% elimination.
- Validity criteria fulfilled:
- yes
- Interpretation of results:
- inherently biodegradable
- Conclusions:
- Acetoacetamide (30% solution) is inherently biodegradable under the conditions of the zahn-Wellens Test.
- Executive summary:
A 30% aequous solution of acetoacetamide was tested for inherent biodegradation in the Zahn-Wellens-test by measuring the DOC disappearance. During the first 7 days of the test the DOC exhaustion achieved > 70% of the carbon content of the added test substance, but the following day the rate of degradation staye at the plateau in the range 70 - 72%. The results were confirmed by additionally conducted COD control analyzes. COD at the start was 510 mg/L and 160 mg/L after 28 days, corresponding to an elimination of about 69%.
Acetoacetamide (30% solution) is inherently biodegradable under the conditions of the zahn-Wellens Test.
Reference
Description of key information
Acetoacetamide (30% solution) is inherently biodegradable under the conditions of the zahn-Wellens Test.
Key value for chemical safety assessment
- Biodegradation in water:
- inherently biodegradable
- Type of water:
- freshwater
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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