Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 816-285-7 | CAS number: 1263133-33-0
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
The test substance is hydrolytically stable at pH 4, 7, and 9. Hydrolysis did not occur at these pHs when tested at 50°C. The hydrolytic half-life of the test substance was > 1 year. The test substance is susceptible to photolysis in pH 7 sterile buffer and natural water under irradiation using a xenon arc lamp to simulate natural sunlight. The photolysis half-life was 50.6 hours in pH sterile buffer and 67 hours in sterile natural water. In each of the irradiated test systems, it was demonstrated that [14C]-test substance degraded under irradiation. One major photodegradation product, identified as IN-RUB93, was detected in all irradiated test systems. This metabolite increased over the course of the study. Unidentified components consisted of multiple degradation products with no individual component accounting for >5% AR. The test substance was stable in the dark control samples under experimental conditions. The test substance dissipated slowly from the soil under anaerobic conditions. The DT50 and DT90 values for the test substance were 302.7 and 1005.6 days respectively. Analysis of soil extracts demonstrated that there were no major metabolites of >5% AR formed during the aerobic and anaerobic incubation period. Minor metabolites, IN-RPD47 and IN-SBY68 were observed at levels less than 5% AR. The rate of aerobic degradation was measured in several different soils. The DT50s in those soils ranged from 52.9 to 133.4 days. Two soil metabolites, IN-SBY68 and IN-RPD47 formed under aerobic conditions at >5% but <10% AR. In a separate study, when exposed to artificial sunlight under laboratory conditions, the test substance degraded photolytically on soil. The DT50 and DT90 values for the test substance in irradiated system were 12.1 days and 40.1 days, respectively forming major metabolites IN-RPA-19 and IN-Y2186 at >10% AR.
The test substance does not meet the criteria to be classified as readily biodegradable. In water the test substance degraded 4.6% after 28 days. In simulation tests in water and sediments, the test substance degraded slightly in the water compartment and partitioned to the sediment where it was further degraded to other metabolites that were eventually incorporated into the sediment as non-extractable residue. Multiple metabolites were observed in the water/sediment systems none of which accounted for more than 5% radioactivity. The DT50 in the water phase was 22.9 -67.3 days. Once in the sediment, the test substance degraded with an overall whole system DT50 of 282.9 -692.1 days.
The vapour pressure and Henry’s law constant of the test substance indicate that it has no potential to volatilize and therefore could not have any global warming potential (GWP), ozone depleting potential (ODP), photochemical ozone creation potential (POCP) or be expected to accumulate in the troposphere. The test substance is not listed in Annex I to Regulation (EC) No 2037/2000 of the European Parliament and of the Council of 29 June 2000 on substances that deplete the ozone layer and its subsequent amendments.
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.