Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 238-518-6 | CAS number: 14513-34-9
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
There are no reliable aquatic toxicity data available for the registration substance, therefore good quality data for the structurally-related substance, 3-(chlorodimethylsilyl)propyl methacrylate (CAS 24636-31-5), have been read across.
Reliable short-term toxicity tests results are available for freshwater invertebrates (Daphnia magna) and algae (Pseudokirchneriella subcapitata) for the read-across substance 3-(chlorodimethylsilyl)propyl methacrylate (CAS 24636-31-5). The relevant short-term values are:
Daphnia: EC50 (48 h): 0.573 mg/l (expressed in terms of geometric mean measured concentration of the hydrolysis products, sum of 3-[hydroxy(dimethyl)silyl]propyl methacrylate (monomeric silanol) and 1,1,3,3-tetramethyldisiloxane-1,3-diyl)dipropane-1,3-diyl dimethacrylate (CAS 18547-93-8, EC 242-419-3) (siloxane dimer))
Algae: EC50 (72 h): 20.2 mg/l; ErC10 4.78 mg/l (expressed in terms of geometric mean measured concentration of the hydrolysis products, sum of 3-[hydroxy(dimethyl)silyl]propyl methacrylate (monomeric silanol) and 1,1,3,3-tetramethyldisiloxane-1,3-diyl)dipropane-1,3-diyl dimethacrylate (CAS 18547-93-8, EC 242-419-3) (siloxane dimer))
The very rapid hydrolysis of the tested substance (half-life <5 min at pH 7 and 20-25 °C) is consistent wth the analytical evidence that the test organisms in each test were exposed primarily to the hydrolysis products, 3-[hydroxy(dimethyl)silyl]propyl methacrylate (monomeric silanol) and 1,1,3,3-tetramethyldisiloxane-1,3-diyl)dipropane-1,3-diyl dimethacrylate (CAS 18547-93-8, EC 242-419-3) (siloxane dimer).
In view of the test media preparation method, pH adjustment and exposure regime it is likely that the test organisms were exposed predominantly to the hydrolysis products (monomeric silanol) and both dissolved and undissolved condensation products (siloxane dimer) of the tested substance. The study was supported by analysis of these hydrolysis products which demonstrates the complete hydrolysis of the chlorosilane group and shows that under the conditions of the test a high proportion of the hydrolysis products are present in the form of dimeric siloxane (at a concentration well in excess of its predicted limit of solubility).
It is to be expected that at higher concentrations, dimeric siloxane condensation products can form from aqueous solutions of the monomeric silanol. There is some evidence of undissolved material (precipitated products) in the study report for this test, and therefore physical effects may have contributed to some extent to the effects in these tests. The use of the E(L)C50 values as a measurement of intrinsic toxicity represents a conservative interpretation of the test findings.
Refer to IUCLID Section 6 endpoint summary for further discussion of the approach to chemical safety assessment and justification for read across.
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.