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Diss Factsheets
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EC number: 916-914-6 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
- Endpoint:
- toxicity to aquatic algae and cyanobacteria
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- From July 20, 1993 to August 30, 1993
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- test procedure in accordance with generally accepted scientific standards and described in sufficient detail
- Principles of method if other than guideline:
- ABC Protocol No. 9207 as approved by CIBA-GEIGY, Ltd. and the ABC Laboratories' study director
- GLP compliance:
- yes
- Details on test solutions:
- - Source (laboratory, culture collection): Department of Botany, Culture Collection of Algae, University of Texas at Austin
- Test organisms (species):
- Scenedesmus sp.
- Details on test organisms:
- - Test vessel: 250-mL Erlenmeyer flask
- Test volume: 100 mL
- No. of vessels per concentration (replicates): 3
- No. of vessels per control (replicates): 3
- Light intensity and quality: approximately 8600 lux - Test type:
- static
- Total exposure duration:
- 72 h
- Nominal and measured concentrations:
- Nominal concentrations: Control (0.0), Vehicle Blank (acetone), 0.10, 1.0 and 10 mg/L
- Details on test conditions:
- - Test vessel: 250-mL Erlenmeyer flask
- Test volume: 100 mL
- No. of vessels per concentration (replicates): 3
- No. of vessels per control (replicates): 3
- Light intensity and quality: approximately 8600 lux - Duration:
- 72 h
- Dose descriptor:
- EC50
- Effect conc.:
- > 10 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- cell number
- Conclusions:
- According to ABC Protocol No. 9207 and the ABC Laboratories' study director, the EC50 and the NOEC of TINUVIN 109 was greater than 10 mg/L and 10 mg/L respectively.
- Executive summary:
This test using the procedures outlined in ABC Protocol No. 9207 as approved by CIBA-GEIGY, Ltd. (1993) and the ABC Laboratories' study director (1993). A 72-hour screen with Scenedesmus subspicatus exposed to TINUVIN 109 was conducted at test concentrations of 0.10, 1.0, and 10 mg/L along with a control and vehicle blank (acetone). Test concentrations were based on the solubility of TINUVIN 109 in algae nutrient media. The results as below:
1) 72-hour EC50 was greater than 10 mg/L (95% confidence limits could not be determined)
2) 72-hour no-observed effect concentration was determined to be 10 mg/L
Reference
A 72-hour screen with Scenedesmus subspicatus exposed to TINUVIN 109 was conducted at test concentrations of 0.10, 1.0, and 10 mg/L along with a control and vehicle blank (acetone). Test concentrations were based on the solubility of TINUVIN 109 in algae nutrient media. Logarithmic phase growth was confirmed at 72 hours with a mean count of 7.3 × 105and 4.5 × 105cells/mL in the control and vehicle blank replicates, respectively, that were 52- and 26-fold increases, respectively, from the initial 1.4 × 104and 1.7 × 104cells/mL. After 72 hours, algal cell counts for the 0.10-, 1.0-, and 10-mg/L test levels were 142, 133, and 91 % of the vehicle blank population, respectively. No oily surface film was noted in the 10 mg/L test solution at 72 hours.
Description of key information
For Scenedesmus subspicatus, the 72-hour EC50 of TINUVIN 109 was greater than 10 mg/L and the NOEC of TINUVIN 109 was 10 mg/L .
Key value for chemical safety assessment
- EC10 or NOEC for freshwater algae:
- 10 mg/L
Additional information
A 72-hour screen with Scenedesmus subspicatus exposed to TINUVIN 109 was conducted at test concentrations of 0.10, 1.0, and 10 mg/L along with a control and vehicle blank (acetone). Test concentrations were based on the solubility of TINUVIN 109 in algae nutrient media. The results as below:
1) 72-hour EC50 was greater than 10 mg/L (95% confidence limits could not be determined)
2) 72-hour no-observed effect concentration was determined to be 10 mg/L
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