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Diss Factsheets
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EC number: 201-891-0 | CAS number: 89-25-8
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
The EC50 on Daphnia magna after 48 h of exposure to the test item under semi-static conditions was calculated to be 10.3 mg/l (Confidence interval : 8.84 - 12.1 mg/L). The NOEC was 2.83 mg/L.
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 10.3 mg/L
Additional information
The acute toxicity of the test item to Daphnia magna was tested according to the OECD guideline 202 and GLP.
According to the properties of the test item, the study was conducted in the dark and in semi-static conditions over a period of 48 hours. 20 daphnies were exposed to the following nominal concentrations 2.5 - 5 - 10 - 20 - 40 - 80 mg/L , and the control.
The concentrations of the test item were verified by LC-MS/MS at the start of the exposure (0 and 24 h) and at the end of each exposure interval (24 and 48h) in all concentrations and the control. The measured concentrations were within 95 to 112% of the nominal concentrations at the start of the exposure. At the end of the exposure they strongly decreased with decreasing nominal concentrations resulting in a range of 101% to < LOD of nominal values. The geometric mean measured concentration were calculated to be : 0.293 - 2.83 - 8.59 - 19.4 - 39.4 - 80.6 mg/L.
The water quality parameter (pH, oxygen) measured at the start and at the end of exposure were within the acceptable limits. The validity criteria of the OECD Guideline 202 were fulfilled.
The NOEC of the test item was 2.83 mg/L. The EC50 on Daphnia magna after 48 h of exposure to the test item under semi-static conditions was calculated to be 10.3 mg/l (Confidence interval : 8.84 - 12.1 mg/L).
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