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Diss Factsheets
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EC number: 207-997-3 | CAS number: 504-63-2
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- comparable to guideline study with acceptable restrictions
- Remarks:
- Valid study with limited documentation.
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- OECD Guideline 202 (Daphnia sp. Acute Immobilisation Test)
- Deviations:
- not specified
- Qualifier:
- according to guideline
- Guideline:
- other: DIN 38412, Part II, German Institute of Standardization
- GLP compliance:
- not specified
- Analytical monitoring:
- not specified
- Details on sampling:
- No data
- Vehicle:
- not specified
- Details on test solutions:
- No data
- Test organisms (species):
- Daphnia magna
- Details on test organisms:
- TEST ORGANISM
- Common name: Daphnia
- Age at study initiation (mean and range, SD): 6-24 h old
- Feeding during test: No
- Test type:
- static
- Water media type:
- freshwater
- Total exposure duration:
- 48 h
- Hardness:
- 2.4 mmol/L
- Test temperature:
- 20°C
- pH:
- 7.8-8.2
- Dissolved oxygen:
- No data
- Nominal and measured concentrations:
- No data
- Details on test conditions:
- TEST SYSTEM
- Test vessel: beakers
- Type (delete if not applicable): closed - ground-glass stoppers
- Size: 2-50 mL, fill volume: 20 mL
- No. of organisms per vessel: 10
- No. of vessels per concentration: 2
TEST MEDIUM / WATER PARAMETERS
- Source/preparation of dilution water: concentration steps of the test solution were selected as to give 3-4 EC values in a range between EC0 and EC100.
- Ca/mg ratio: 4:1 - Reference substance (positive control):
- yes
- Remarks:
- 70 substances tested, including phenols, anilines and aliphatic compounds
- Duration:
- 24 h
- Dose descriptor:
- EC0
- Effect conc.:
- 3 644 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mobility
- Duration:
- 24 h
- Dose descriptor:
- EC50
- Effect conc.:
- 8 285 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mobility
- Remarks on result:
- other: 7357-9331 mg/L
- Duration:
- 24 h
- Dose descriptor:
- EC100
- Effect conc.:
- > 10 000 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mobility
- Duration:
- 48 h
- Dose descriptor:
- EC0
- Effect conc.:
- 2 603 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mobility
- Duration:
- 48 h
- Dose descriptor:
- EC50
- Effect conc.:
- 7 417 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mobility
- Remarks on result:
- other: 6430-8555 mg/L
- Duration:
- 48 h
- Dose descriptor:
- EC100
- Effect conc.:
- > 10 000 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mobility
- Details on results:
- - The ratios between the 24 h EC50 and the 48 h EC50 indicate the reduction of the concentration having a harmful effect on the daphnids if the test period is increased from 24 to 48 h.
- Defined concentrations of a substance, a specific percentage of daphnids were incapable of swimming at the end of the test period. - Results with reference substance (positive control):
- No data
- Validity criteria fulfilled:
- yes
- Conclusions:
- 48-hour EC50: 7417 mg/L
- Executive summary:
1,3-Propanediol was tested for acute toxicity to daphnids in a static, 48-hour test. The 48-hour EC50 was determined to be 7417 mg/L based on nominal test concentrations.
Reference
Test was considered valid when fewer than 10% of the animals in the control solutions were unable to swim when the pH was not below 7 and O2 value was not below 4 mg/L.
Description of key information
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 7 417 mg/L
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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