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EC number: 440-770-9 | CAS number: 371921-63-0
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Water solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 105 (Water Solubility)
- Version / remarks:
- adopted July 27, 1995
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.6 (Water Solubility)
- Version / remarks:
- EEC Publication No. L383, December 1992
- GLP compliance:
- yes
- Type of method:
- flask method
- Key result
- Water solubility:
- 6.7 g/L
- Conc. based on:
- test mat.
- Incubation duration:
- >= 24 - <= 72 h
- Temp.:
- 20 °C
- Remarks on result:
- completely miscible
- Details on results:
- The saturation concentration of BLUE GS 5664.80 at room temperature was estimated by a simplified flask method in the preliminary test to be higher than 10^(-2) g/L Therefore, the flask shaking test was performed.
The solubility of BLUE GS 5664.80 in water was determined after a shaking time of 24 hours, 48 hours and 72 hours, respectively at 30 °C. Afterwards the samples were equilibrated for 24 hours at 20.0 °C. The concentrations determined after an equilibration period of 72 hours shows a relevant degradation of the main peak. This indicates a degradation of the test item BLUE GS 5664.80 in water. The concentration of the water solubility was calculation using
the measured results of the samples equilibrated for 24 hours and 48 hours. The concentrations measured differ by less than 15 %. Therefore, the study is considered to be valid. The measured concentrations after incubation time of 72 hours showed a smaller solubility.
In conclusion, the water solubility of BLUE GS 5664.80 at 20.0 °C was determined to be 6.7 g/1 (standard deviation± 0.4 g/l).
The water solubility was not corrected for the purity of the test item. - Conclusions:
- The water solubility of BLUE GS 5664.80 at 20.0 °C was determined to be 6.7 g/l (standard deviation± 0.4 g/l).
- Executive summary:
The water solubility of BLUE GS 5664.80 has been determined in the current study performed following OECD TG 105 according to GLP.
The saturation concentration of BLUE GS 5664.80 at room temperature was estimated by a simplified flask method in the preliminary test to be higher than 10^(-2) g/1. Therefore, the flask shaking test was performed.
The solubility of BLUE GS 5664.80 in water was determined after a shaking time of 24 hours, 48 hours and 72 hours, respectively at 30 °C. Afterwards the samples were equilibrated for 24 hours at 20.0 °C. The concentrations determined after an equilibration period of 72 hours shows a relevant degradation of the main peak. This indicates a degradation of the test item BLUE GS 5664.80 in water. The concentration of the water solubility was calculation using the measured results of the samples equilibrated for 24 hours and 48 hours. The concentrations measured differ by less than 15 %. Therefore, the study is considered to be valid. The measured concentrations after incubation time of 72 hours showed a smaller solubility.
The water solubility of BLUE GS 5664.80 at 20.0 °C was determined to be 6.7 g/l (standard deviation± 0.4 g/l).
Reference
Data of the performance of the water solubility test
Sample solution no. |
1 |
2 |
3 |
4 |
5 |
6 |
Weighed sample of the test item (g) |
0.83 |
0.97 |
0.68 |
0.66 |
0.64 |
0.69 |
Added volume of water (ml) |
20.0 |
20.0 |
20.0 |
20.0 |
20.0 |
20.0 |
Agitation time at 30°C (hours) |
72 |
72 |
48 |
48 |
24 |
24 |
Equilibration time at 20°c(hours) |
24 |
24 |
24 |
24 |
24 |
24 |
pH value of test item solution |
9.52 |
9.54 |
9.59 |
9.65 |
9.61 |
9.60 |
Dilution factor before quantification (0.5 ml to 100 ml) |
200 |
200 |
200 |
200 |
200 |
200 |
Results of the water solubility of BLUE GS 5664.80
Sample No. |
Shaking time at30 °C |
Concentration analysed[mg/I] |
Concentration calculated [g/l] |
Water solubility calculated [g/l] |
1 |
72 |
29.2 |
5.84 |
6.7 SD =±0.4 |
2 |
72 |
27.7 |
5.55 |
|
3 |
48 |
35.6* |
7.13* |
|
4 |
48 |
32.8* |
6.57* |
|
5 |
24 |
30.9* |
6.18* |
|
6 |
24 |
34.8* |
6.96* |
* The mean value was calculated from the bold values. The smaller concentration of the test item after an incubation time of 72 hours indicates a degradation of BLUE GS 5664.80 and was therefore not used for the calculation.
Description of key information
Key value for chemical safety assessment
- Water solubility:
- 6.7 g/L
- at the temperature of:
- 20 °C
Additional information
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