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EC number: 204-976-0 | CAS number: 130-14-3
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
- Endpoint:
- activated sludge nitrification inhibition testing
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Data is from authoritative database
- Justification for type of information:
- Data is from authoritative database
- Qualifier:
- according to guideline
- Guideline:
- other: Refer below principle
- Principles of method if other than guideline:
- To evaluate Toxicity of test material Sodium 1-Naphthalenesulfonate on microorganism
- GLP compliance:
- not specified
- Specific details on test material used for the study:
- IUPAC: Sodium 1-Naphthalenesulfonate
Mol. formula: C10H7NaO3S
Molecular Weight:230.218
InChI:1S/C10H8O3S.Na/c11-14(12,13)10-7-3-5-8-4-1-2-6-9(8)10;/h1-7H,(H,11,12,13);/q;+1/p-1
Smiles:c12c(S(=O)(=O)[O-])cccc1cccc2.[Na+] - Details on test solutions:
- water solution of test material and AS mixed before experiment and aerated for 10 min
- Test organisms (species):
- activated sludge
- Details on inoculum:
- Source: pilot activated sludge plant at Water Research Center, Swindon, UK
- Test type:
- static
- Water media type:
- freshwater
- Limit test:
- no
- pH:
- 7.0 - 8.0
- Nominal and measured concentrations:
- 50 - 200 mg/l
- Details on test conditions:
- -in vitro; samples of actively-nitrifying sludge mixed liquor, suspended solids, SS in concentration 2000 mg/l; standard procedure for assessment of nitrification inhibition, respiration rate of AS determined from the rate of O2 depletion measured by oxygen electrode
- Reference substance (positive control):
- not specified
- Dose descriptor:
- IC50
- Effect conc.:
- 926 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- inhibition of nitrification rate
- Remarks on result:
- other: slightly inhibited nitrification
- Dose descriptor:
- other: IC20
- Effect conc.:
- 195 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- inhibition of nitrification rate
- Remarks on result:
- other: no other details available
- Validity criteria fulfilled:
- not specified
- Conclusions:
- The inhibition concentration (IC50) for the nitrifying bacteria was observed to be 926 mg/l
- Executive summary:
Toxicity of microorganism was evaluated for the test material Sodium 1-Naphthalenesulfonate . Water solution of test material and AS mixed before experiment and aerated for 10 min. Activated sludge having nitrifying bacteria were used obtained from a pilot activated sludge plant at Water Research Center, Swindon. In vitro; samples of actively-nitrifying sludge mixed liquor, suspended solids, SS in concentration 2000 mg/l; standard procedure for assessment of nitrification inhibition, respiration rate of AS determined from the rate of O2 depletion measured by oxygen electrode. The nominal concentrations tested were 50 - 200 mg/l. The inhibition concentration (IC50) for the nitrifying bacteria was observed to be 926 mg/l , the (IC20) was observed to be 195 mg/l. Slightly inhibited nitrification was observed.
Reference
Description of key information
Toxicity to microorganism:
Toxicity of microorganism was evaluated for the test material Sodium 1-Naphthalenesulfonate . Water solution of test material and AS mixed before experiment and aerated for 10 min. Activated sludge having nitrifying bacteria were used obtained from a pilot activated sludge plant at Water Research Center, Swindon. In vitro; samples of actively-nitrifying sludge mixed liquor, suspended solids, SS in concentration 2000 mg/l; standard procedure for assessment of nitrification inhibition, respiration rate of AS determined from the rate of O2 depletion measured by oxygen electrode. The nominal concentrations tested were 50 - 200 mg/l. The inhibition concentration (IC50) for the nitrifying bacteria was observed to be 926 mg/l , the (IC20) was observed to be 195 mg/l. Slightly inhibited nitrification was observed.
Key value for chemical safety assessment
- EC50 for microorganisms:
- 926 mg/L
Additional information
Toxicity to microorganism:
Toxicity of microorganism was evaluated for the test material Sodium 1-Naphthalenesulfonate . Water solution of test material and AS mixed before experiment and aerated for 10 min. Activated sludge having nitrifying bacteria were used obtained from a pilot activated sludge plant at Water Research Center, Swindon. In vitro; samples of actively-nitrifying sludge mixed liquor, suspended solids, SS in concentration 2000 mg/l; standard procedure for assessment of nitrification inhibition, respiration rate of AS determined from the rate of O2 depletion measured by oxygen electrode. The nominal concentrations tested were 50 - 200 mg/l. The inhibition concentration (IC50) for the nitrifying bacteria was observed to be 926 mg/l , the (IC20) was observed to be 195 mg/l. Slightly inhibited nitrification was observed.
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