Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: - | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
Additional information
The available ecotoxicology studies (acute tests with fish, invertebrates, algae and micro-organism) were performed with FAT 41'030/A, a structural analogue of FAT 41045. Both substances are very similar in their chemical structure and, as demonstrated, in a number of physicochemical properties. Therefore, the use of these studies with FAT 41030 for read-across is considered to be appropriate.
The acute toxicity to zebrafish was determined according to OECD 203 and in compliance with GLP in a 96 hour semi-static test. No mortality of fish was recorded in the control and the nominal test concentration of 100 mg/L FAT 41030/A during the 96 hour exposure period. No sublethal effects such as changes in swimming behaviour, respiratory function, pigmentation or loss of equilibrium were observed in control animals or those assigned to 100 mg/L test concentration during the 96 hour test period. Thus, the LC50(96 h) of FAT 41030/A was determined to be greater than 100 mg/L based on the nominal concentrations.
The acute toxicity to Daphnia magna was determined according to OECD 202, Part 1, and 92/69/EEC, Annex L 383 A, C.2. in compliance with GLP. Immobilisation of the Daphnia or sublethal effects were not evident in the controls or at any of the test item concentrations. Thus, the EC50(48 h) to Daphnia magna was greater than the saturation concentration (> 100 mg/L nominal).
The influence of the test item on the growth of the green algal speciesScenedesmus subspicatusCHODAT was investigated in a 72-hour static test according to EU Commission Directive 92/69/EEC, C.3 of 1992, and OECD Guideline 201 of 1984 in compliance with GLP. On all counting dates, mean algal cell densities in the test medium were almost identical or even slightly higher than those in the parallel control cultures. Thus, the test item FAT 41'030/A clearly had no inhibitory effect on the growth ofSeenedesmus subspieatusduring the 72 hour exposure period in the undiluted filtrate at a loading rate of 100 mg/L. The 72-hour EC50for mean algal biomass and mean growth rate were higher than the loading rate of 100 mg/L.
The Bacteria toxicity test was performed according to OECD 209 and 67/548/EEC, Part C in compliance with GLP. At all applied test concentrations, the test item showed no significant toxic effects (% inhibition of the respiration rate <15 %) to the activated sludge. The respiration rates were in the same range as determined in the controls. Hence, the IC50and the IC20values for the test item were greater than 1000 mg/L.
In conclusion there was no indication of acute toxicity of FAT41'030/Ato the aquatic environment.Due to the poor water solubility of FAT 41'030/A (< 0.3 mg/L), the exposure to the aquatic compartment is negligible and no further tests are necessary or proposed.The same is concluded for FAT 41045 the structural analogue of FAT 41030.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.