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EC number: 248-451-4 | CAS number: 27425-55-4
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
Additional information
Biodegradation
Biodegradation in water
Biodegradation in water ability was predicted(SSS QSAR Prediction model, 2016) for the test compound 3 -(1H-benzimidazol-2 -yl)-7 -(diethylamino)-2 -benzopyrone (CAS no. 27425 -55 -4) using the SSS QSAR prediction model. The inherent biodegradability of the test substance
3-(1H-benzimidazol-2-yl)-7-(diethylamino)-2-benzopyrone was estimated as 84.56% by using DOC removal parameter. This result indicates that 3-(1H-benzimidazol-2-yl)-7-(diethylamino)-2-benzopyrone was estimated to be readily biodegradable in water.
Biodegradation in water and sediment
Estimation Programs Interface (EPI) Suite (2016) prediction model was run to predict the half-life in water and sediment for the test compound3-(1H-Benzimidazol-2-yl)-7-(diethylamino)-2-benzopyrone(CAS no. 27425-55-4). Half life period of 3-(1H-benzimidazol-2-yl)-7-(diethylamino)-2-benzopyrone is estimated to be 37.5 days (900 hrs.) while in sediment it is 337.5 days (8100 hrs). Based on these half life values of 3-(1H-benzimidazol-2-yl)-7-(diethylamino)-2-benzopyrone, it is concluded that the chemical is not persistent in water and persistent in sediment.
Biodegradation in soil
Based on EPI prediction Level III Fugacity Model (EPI suite, 2016), the estimated half life period of 3 -(1H-benzimidazol-2 -yl)-7 -(diethylamino)-2- benzopyrone(CAS no. 27425-55-4)in soil was obtained to be 75 days (1800 hrs). Based on this half life value of 3 -(1H-benzimidazol-2 -yl)-7 -(diethylamino)-2-benzopyrone, it is concluded that the chemical is not persistent in the soil environment.
Adsorption / desorption:
Various predicted data for the target chemical 3-(1H-benzimidazol-2-yl)-7-(diethylamino)-2-benzopyrone (Cas no. 27425-55-4) and read across chemical N,N-diethylaniline(Cas no. 91-66-7) were reviewed to summarize the following information:
Predicted sources i.e EPI Suite and Chemspider,Scifinder (Advanced Chemistry Development (ACD/Labs) Software V11.02) database indicate that the test substance 3-(1H-benzimidazol-2-yl)-7-(diethylamino)-2-benzopyrone has a strong sorption to soil and sediment and therefore have negligible migration potential to groundwater.
With following Koc values:
EPI SUITE - 13000 (Log Koc=4.1139)
Scifinder (Advanced Chemistry Development (ACD/Labs) Software V11.02) - Koc= 5590 (log Koc= 3.7474) at pH 6, Koc= 6100 (log Koc= 3.7853) at pH 7
Chemspider - 7559.93 (log Koc =3.8785)
Other experimental study for read across N,N-diethylaniline (Cas no. 91-66-7) indicate that the The adsorption coefficient Koc in soil and in sewage sludge N,N-diethylaniline (CAS No. 91-66-7) was determined by the Reverse Phase High Performance Liquid Chromatographic method according to OECD Guideline No. 121 for testing of Chemicals. The reference substances were chosen according to structural similarity with the test substance and calibration graph was prepared. The Log Koc value was found to be 3.594 ± 0.003at 25°C
Thus overall all results indicate that the test substance 3-(1H-benzimidazol-2-yl)-7-(diethylamino)-2-benzopyrone (Cas no. 27425-55-4) have tendency strong sorption to soil and sediment and therefore have negligible migration potential to groundwater.
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