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EC number: 264-129-6 | CAS number: 63405-85-6
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
- Endpoint:
- biodegradation in water: inherent biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- Experiment start date - 09 October 1990; Experiment end date - 14 November 1990; Study completion date - 14 November 1991.
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 302 B (Inherent biodegradability: Zahn-Wellens/EMPA Test)
- Deviations:
- yes
- Remarks:
- Sludge concentration: 1000 mg/l
- Qualifier:
- according to guideline
- Guideline:
- other: EEC Directive, L133 (pp.99-105) Volume 31, May 88 (ISSN 0378-6978)
- Deviations:
- yes
- Remarks:
- Sludge concentration: 1000 mg/l
- Qualifier:
- according to guideline
- Guideline:
- other: ISO Method 8192 B
- Deviations:
- yes
- Remarks:
- Sludge concentration: 1000 mg/l
- GLP compliance:
- yes
- Specific details on test material used for the study:
- Name: FAT 20004/H
Storage: room temperature
Appearance: solid - Oxygen conditions:
- not specified
- Inoculum or test system:
- other: Sludge of a domestic sewage treatment plant
- Details on inoculum:
- Sludge of a domestic sewage treatment plant (ARA-Rhein) collected on 16.10.90
- Duration of test (contact time):
- 28 d
- Initial conc.:
- 100 mg/L
- Based on:
- DOC
- Parameter followed for biodegradation estimation:
- DOC removal
- Details on study design:
- Test concentration: 100 mg/l DOC nominal
Water / Nutrient According to the specification of the EEC L133
(pp.99-105) Volume 31 resp. OECD Method 302B.
Temperature: 22 ± 3 °C
Duration: 28 days
Lighting: Indirect daylight
Estimation technique: TOC/DOC SHIMADZU TOC-500 - Reference substance:
- diethylene glycol
- Remarks:
- Fluka Nr. 32170
- Parameter:
- % degradation (DOC removal)
- Value:
- 97.75
- Sampling time:
- 28 d
- Remarks on result:
- other: Adsorption after 3 hours: 54.3 %
- Details on results:
- Elimination measured as DOC (mg/l) after 28 days corrected by the blank control is: 97.75 % (average of 2 tests running in parallel)
Adsorption after 3 hours: 54.3 % - Results with reference substance:
- Biodegradation corrected by the blank control and measured as DOC (mg/1) is: 94.8 % (28th day).
- Validity criteria fulfilled:
- yes
- Interpretation of results:
- inherently biodegradable
- Conclusions:
- The biodegradation of the test substance FAT 20004/H after 28 days was 97.75 %
- Executive summary:
The inherent biodegradability of FAT 20004/H was determined in a Zahn-Wellens / EMPA Test according to the OECD Guideline for Testing of Chemicals, No. 302B, 1992. The reference substance used was Diethylene glycol in the test.
Biodegradation:
The biodegradation of the test substance FAT 20004/H after 28 days was: 97.75 %
Total Elimination: (regarding the adsorption and the biodegradation)
The total elimination of the test substance FAT 20004/H after 28 days was: 97.75 % (average of 2 tests running in parallel)
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- Experiment start date - 01 November 1990; Experiment end date - 11 November 1990; Study completion date - 04 February 1991.
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- other: EEC, Annex V, Part. C.8, corresponding to DEV H-5 (a2), Ausgabe 1966
- GLP compliance:
- yes
- Specific details on test material used for the study:
- Test substance: FAT 20004/H
Storage: room temperature
Appearance: solid - Oxygen conditions:
- not specified
- Inoculum or test system:
- other: mixed culture of bacteria (effluent of a Husman laboratory apparatus)
- Duration of test (contact time):
- 2 h
- Parameter followed for biodegradation estimation:
- O2 consumption
- Details on study design:
- Experimental conditions
Test concentration - 1, 5, 10, 20, 50, 100, 200 and 500 mg/l
Temperature - 22 ± 2 °C
Duration - 5 days - Reference substance:
- benzoic acid, sodium salt
- Parameter:
- other: BOD was determined
- Remarks on result:
- other: BOD
- Parameter:
- BOD5
- Value:
- 0 mg O2/g test mat.
- Results with reference substance:
- The BOD5 of Sodium benzoate, corrected by the blank control is:
for 4 mg/l reference substance = 1275 mg/g O2
for 5 mg/l reference substance = 1280 mg/g O2 - Validity criteria fulfilled:
- not specified
- Interpretation of results:
- under test conditions no biodegradation observed
- Conclusions:
- The BOD of FAT 20004/H is 0 mg O2/g test mat.
- Executive summary:
The biochemical oxygen demand of FAT 20004/H is determined by measuring the dissolved oxygen concentration before and after 5 days incubation at 20 °C in different test concentrations diluted in water saturated with dissolved oxygen that contains a seed of micro-organisms. The test was carried out according to ISO 5815 Second Edition 1989-08-01 (E) corresponding to 92 / 69 / EEC C.5. The test substance was tested in concentrations from about 1 to 500 mg/I. The reference substance used was Sodium benzoate (>99,5 %, FLUKA Nr. 71295). The BOD of FAT 20004/H is 0 mg O2/g test mat.
The BOD5 of Sodium benzoate, corrected by the blank control is: for 4 mg/l reference substance = 1275 mg/g O2; for 5 mg/l reference substance = 1280 mg/g O2. In another study, the BOD for FAT 20004/H was determined to be 1488 mg/g O2. The resultant BOD:COD ratio was calculated to be zero, indicating FAT 20004/H is not biodegradable.
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- Experiment start and end date - 08 November 1990; Study completion date - 04 February 1991.
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- other: EEC Directive 79-831, Annex V, C.9. according to German DIN-Norm 38*409, H-41, 1 (Dezember 1980)
- Deviations:
- no
- GLP compliance:
- yes
- Specific details on test material used for the study:
- Name: FAT 20004/H
Storage: room temperature
Appearance: solid - Oxygen conditions:
- other: Titration method
- Inoculum or test system:
- other: Titration method
- Duration of test (contact time):
- 2 h
- Parameter followed for biodegradation estimation:
- test mat. analysis
- Reference substance:
- other: KHP (Merck No.4876)
- Remarks on result:
- other: COD was determined
- Parameter:
- COD
- Value:
- 1 488 mg O2/g test mat.
- Results with reference substance:
- The COD of reference substance is 196 mg O2/g test mat.
- Validity criteria fulfilled:
- not specified
- Interpretation of results:
- under test conditions no biodegradation observed
- Conclusions:
- The COD of FAT 20004/H is 1488 mg O2/g test mat.
- Executive summary:
A key study was performed to determine the chemical oxygen demand for FAT 20004/H according to DIN 38409 - H 41-1 (1980) corresponding to EEC Directive 92 / 69 / C.6. (1992). The reference substance was KHP (Merck No.4876). It was tested with 2.5 mg of the test substance. The COD of FAT 20004/H is :1488 mg O2/g test mat. The COD of the reference substance is: 196 mg O2/g test mat. In another study, the BOD of FAT 20004/H was determined to be 0 mg O2/g. The resultant BOD:COD ratio was found to be 0 indicating that the substance is not biodegradable.
Referenceopen allclose all
Experiment 1:
Time | Elimination (%) |
0 hour | 61.9 |
3 hours | 53 |
2 days | 53.6 |
5 days | 91.3 |
7 days | 87.8 |
9 days | 90.3 |
12 days | 93.5 |
14 days | 91.5 |
16 days | 94.2 |
19 days | 100 |
21 days | 100 |
23 days | 100 |
26 days | 100 |
28 days | 100 |
Experiment 2:
Time | Elimination (%) |
0 hour | 66.2 |
3 hours | 55.6 |
2 days | 86.9 |
5 days | 90 |
7 days | 86.6 |
9 days | 87.7 |
12 days | 91.5 |
14 days | 88.6 |
16 days | 95 |
19 days | 100 |
21 days | 100 |
23 days | 100 |
26 days | 100 |
28 days | 100 |
Description of key information
The test substance FAT 20004 can be regarded as non-biodegradable.
Key value for chemical safety assessment
- Biodegradation in water:
- under test conditions no biodegradation observed
Additional information
The inherent biodegradability of the test substance FAT 20004/H was determined in a GLP-compliant study in Zahn-Wellens / EMPA Test according to OECD Guideline 302B. The test substance FAT 20004/H and the reference substance Diethylene glycol, respectively, were tested. The biodegradation of the test substance FAT 20004/H after 28 days was 97.75 %. Individual BOD5 and COD estimation were done in GLP-compliant studies according to ISO 5815 and EEC 92/69/C.6 (1992), respectively. The biochemical oxygen demand of FAT 20004/H was determined by measuring the dissolved oxygen concentration before and after 5 days incubation at 20 °C in different test concentrations diluted in water saturated with dissolved oxygen that contains a seed of micro-organisms. The BOD5 and COD of FAT 20004/H was found to be 0 mg O2/g and 1488 mg O2/g, respectively. Few non-GLP compliant studies performed in the 70’s have reported the following BOD5 and COD values for FAT 20004:
FAT 20004/A: BOD5 = 14 mg/g O2; COD = 1182.40 mg/g O2
FAT 20004/B: BOD5 = 22.5 mg/g O2; COD = 1389.12 mg/g O2
FAT 20004/C: BOD5 = 53 mg/g O2; COD = 1215.16 mg/g O2
FAT 20004/D: BOD5 = 11.4 mg/g O2; COD = 1274.01 mg/g O2
BOD5 = 11 mg/g O2; COD = 933.54 mg/g O2
Relevant is the BOD5/COD quotient which is not >0.5, therefore the substance is not indicative of rapid degradation. Taking into consideration the data from key study and supporting studies, the test substance FAT 20004 can be regarded as non biodegradable.
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