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EC number: 202-974-4 | CAS number: 101-77-9
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Toxicity to terrestrial plants
Administrative data
Link to relevant study record(s)
- Endpoint:
- toxicity to terrestrial plants: long-term
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- guideline study with acceptable restrictions
- Remarks:
- eight deviations from the protocol are listed in this report
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 208 (Terrestrial Plants Test: Seedling Emergence and Seedling Growth Test)
- GLP compliance:
- yes
- Analytical monitoring:
- no
- Details on preparation and application of test substrate:
- Test substance, dissolved in acetone, was applied to coarse sand, which after drying was mixed with the other soil ingredients (agricultural soil 1:1 dw with sand, + potassium hydrogen phosphate 0.166%). Soil was wet, to ca 25%, prior to test.
- Species:
- Avena sativa
- Plant group:
- Monocotyledonae (monocots)
- Test type:
- other: 1. seedling emergence toxicity test 2. survival
- Study type:
- laboratory study
- Substrate type:
- artificial soil
- Total exposure duration:
- 17 d
- Post exposure observation period:
- Emergence occurred within 3 days.
- Test temperature:
- 19-25°C
- pH:
- 7.5-7.8
- Moisture:
- ca 25% prior to test
- Details on test conditions:
- 16h light/8h dark.
- Nominal and measured concentrations:
- Nominal concentrations were 0, 10, 32, 100, 320 and 1000 mg MDA/kg soil (dw)
Determined by range-finding tests. - Species:
- Avena sativa
- Duration:
- 17 d
- Dose descriptor:
- NOEC
- Effect conc.:
- 320 mg/kg soil dw
- Basis for effect:
- seedling emergence
- Species:
- Avena sativa
- Duration:
- 14 d
- Dose descriptor:
- EC50
- Effect conc.:
- 353 mg/kg soil dw
- Basis for effect:
- growth
- Species:
- Avena sativa
- Duration:
- 14 d
- Dose descriptor:
- NOEC
- Effect conc.:
- 100 mg/kg soil dw
- Basis for effect:
- growth
- Species:
- Avena sativa
- Duration:
- 14 d
- Dose descriptor:
- NOEC
- Effect conc.:
- >= 1 000 mg/kg soil dw
- Basis for effect:
- other: survival
- Endpoint:
- toxicity to terrestrial plants: long-term
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- guideline study
- Remarks:
- eight deviations from the protocol are listed in the report.
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 208 (Terrestrial Plants Test: Seedling Emergence and Seedling Growth Test)
- GLP compliance:
- yes
- Analytical monitoring:
- no
- Details on preparation and application of test substrate:
- Test substance, dissolved in acetone, was applied to coarse sand, which after drying was mixed with the other soil ingredients (agricultural soil 1:1 dw with sand, + potassium hydrogen phosphate 0.166%). Soil was wet, to ca 25%, prior to test.
- Species:
- Lactuca sativa
- Plant group:
- Dicotyledonae (dicots)
- Test type:
- other: 1. seedling emergence toxicity test 2. early seedling growth toxicity test 3. survival
- Study type:
- laboratory study
- Substrate type:
- artificial soil
- Total exposure duration:
- 17 d
- Post exposure observation period:
- Emergence occurred within 3 days.
- Test temperature:
- 19-25°C
- pH:
- 7.5-7.8
- Moisture:
- Soil was wet to ca. 25%
- Details on test conditions:
- 16h light/8h dark.
- Nominal and measured concentrations:
- Nominal concentrations were 0, 3.2, 10, 32, 100 and 320 mg MDA/kg soil (dw)
Determined by range-finding tests. - Species:
- Lactuca sativa
- Duration:
- 17 d
- Dose descriptor:
- NOEC
- Effect conc.:
- 100 mg/kg soil dw
- Basis for effect:
- seedling emergence
- Species:
- Lactuca sativa
- Duration:
- 14 d
- Dose descriptor:
- EC50
- Effect conc.:
- 128 mg/kg soil dw
- Basis for effect:
- growth
- Species:
- Lactuca sativa
- Duration:
- 14 d
- Dose descriptor:
- NOEC
- Effect conc.:
- 10 mg/kg soil dw
- Basis for effect:
- growth
- Species:
- Lactuca sativa
- Duration:
- 14 d
- Dose descriptor:
- NOEC
- Effect conc.:
- >= 1 000 mg/kg soil dw
- Basis for effect:
- other: survival
Referenceopen allclose all
Description of key information
After 14 d exposure with the test item EC50 values of 353 mg/kg (Avena sativa) and 128 mg/kg (Latuca sativa) were obtained.
Key value for chemical safety assessment
- Short-term EC50 or LC50 for terrestrial plants:
- 128 mg/kg soil dw
Additional information
There are two reliable studies for two different terrestrial plant species (Avena sativa and Latuca sativa) available which are used to assess the acute toxicity of the test item to terrestrial plants (TNO, 1992). Both studies were conducted according to the OECD guideline 208 and GLP regulations. After 14 d exposure with the test item EC50 values of 353 mg/kg (Avena sativa) and 128 mg/kg (Latuca sativa) were obtained.
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