Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 200-579-1 | CAS number: 64-18-6
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
With high probability acutely not harmful to fish.
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Effect concentration:
- 130 mg/L
Marine water fish
Marine water fish
- Effect concentration:
- 1 700 mg/L
Additional information
Regarding the acute toxicity of formic acid to fish, three studies using freshwater species as well as one study which applied saltwater species are available. A test performed by Fraunhofer on behalf of Kemira Oyi (2005) was identified as key study regarding freshwater fish, as it is a GLP-guideline test including analytical test item verification. The test was performed according to OECD guideline 203 using Danio rerio as test organism. As test substance the analogous substance ammonium formate was used. Statistical evaluation of the endpoint mortality revealed a LC50 (96h) of 130 mg/L, related to the analytically verified nominal concentrations. The low hazard potential is supported by two other valid tests. One supporting study used Leuciscus idus as test species in a static non-GLP approach according to German Industrial Standard DIN 38412 part 15 (BASF AG, 1989). After 96 hours of exposure a LC50 >100 mg/L was estimated for a neutralized sample, related to the nominal concentrations. Non neutralized samples revealed a LC50 between 46.4 mg/L (0% mortality) and 100 mg/L (100% mortality). This effect is clearly pH-dependent as pH values in the samples of the highest concentration were measured to be approx. 3.3. The second supporting study was performed according to GLP and OECD guideline 203 using the analogous substance potassium formate (Huntingdon on behalf of Kemira Oyi, 1992). As test species Oncorhynchus mykiss was applied. In the static approach a LC50 (96h) of 3500 mg/L was estimated, related to the nominal concentrations.
The only available study on marine fish was performed according to a national british guideline using turbot (Scophthalmus maximus) as test species (Huntingdon on behalf of Kemira Oyi, 1992). The GLP-test was conducted with the analogous substance potassium formate as test material. After 96 hours of exposure, a LC50 of 1700 mg/L was estimated, related to the nominal concentrations.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.