Registration Dossier
Registration Dossier
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EC number: 203-742-5 | CAS number: 110-16-7
Acute Toxicity: dermal
Administrative data
- Endpoint:
- acute toxicity: dermal
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Data taken from OECD SIDS Draft for Maleic Acid
Data source
Referenceopen allclose all
- Reference Type:
- secondary source
- Title:
- Material Safety Data Sheet
- Author:
- Eastman Kodak
- Year:
- 1 973
- Bibliographic source:
- cited in OECD SIDS Draft Maleic Acid 01.09.2005
- Reference Type:
- secondary source
- Title:
- Material Safety Data Sheet
- Author:
- Eastman Kodak
- Year:
- 1 973
- Bibliographic source:
- cited in Bibra International Ltd: Toxicity Profile - Maleic Acid (1990)
- Reference Type:
- secondary source
- Title:
- Material Safety Data Sheet
- Author:
- Eastman Kodak
- Year:
- 1 973
- Bibliographic source:
- cited in Patty F.: Industrial Hygiene and Toxicology, 1981
Materials and methods
- Principles of method if other than guideline:
- Unspecified study to determine the acute dermal toxicity.
- GLP compliance:
- not specified
- Test type:
- other: no data
Test material
- Reference substance name:
- Maleic acid
- EC Number:
- 203-742-5
- EC Name:
- Maleic acid
- Cas Number:
- 110-16-7
- Molecular formula:
- C4H4O4
- IUPAC Name:
- but-2-enedioic acid
- Details on test material:
- Maleic acid, no data on purity
Constituent 1
Test animals
- Species:
- rabbit
- Strain:
- not specified
- Sex:
- not specified
Administration / exposure
- Type of coverage:
- not specified
- Vehicle:
- not specified
- Duration of exposure:
- no data
- Doses:
- no data
- No. of animals per sex per dose:
- no data
- Control animals:
- not specified
Results and discussion
Effect levels
- Sex:
- not specified
- Dose descriptor:
- LD50
- Effect level:
- 1 560 mg/kg bw
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
