Registration Dossier
Registration Dossier
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EC number: 416-050-5 | CAS number: 87460-09-1 SQ 28,355; SQ 28355
Guidance on Safe Use
Administrative data
First-aid measures
Emergency measure - Inhalation: Remove to fresh air. If signs of toxicity occur, seek
medical attention.
Emergency measure - Eyes: Irrigate affected eye(s) with copious amounts of water, for
at least 15 minutes. Seek immediate medical attention.
Emergency measure - Skin: Remove contaminated clothing. Wash affected area with
copious amounts of water, for at least 15 minutes. If
irritation persists seek medical attention.
Emergency measure - Ingestion: Rinse mouth thoroughly with water if the subject is
conscious. Seek immediate medical attention.
Fire-fighting measures
Recommended extinguishing agent: Use appropriate medium for the underlying cause of fire and
surrounding environment e.g. water or foam.
Product arising from burning: May include carbon monoxide, carbon dioxide
Product determined by test: N
Protective equipment: Fire-fighters must wear full protective clothing including
self contained breathing apparatus.
Accidental release measures
Emergency measures in case of spillage: Protective clothing and respirator must be worn. Collect
material to minimise dust generation; use wet mop, damp
sponge or wet/dry HEPA vacuum. Place collected material
into a suitable container for reclamation or disposal. Spill
area should then be washed and adequately ventilated.
Handling and storage
Handling: When engineering controls are not sufficient to control dust
exposures, approved respiratory protection to EN 136
standard must be worn. For manufacturing areas skin
protection must be provided in the form of Tyvek coveralls
or gowns (or other type of impervious material) along with
latex or other impermeable gloves. Gloves must be changed
regularly and removed after overt contamination. Double
gloving is recommended where potential skin contact could
occur. Rubber, neoprene or other gloves are required if
solvents, corrosives or other chemicals are present.
Chemical safety glasses must be worn if a full face
respirator is not being worn.
Storage: Store in a dry place in sealed unbreakable containers ie.
fibre drums lined with polythene, away from heat sources.
Packaging of the substance and or preparation: Package in UN approved polythene lined fibre drums (47 x 72
cm), maximum capacity 39 kg maximum.
Transport information
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Marine transport (UN RTDG/IMDG)
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Air transport (UN RTDG/ICAO/IATA)
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Special provisions / remarks
- Remarks:
- Transport code: No UN number has been assigned.
Transport: Use normal procedures for transport of industrial chemicals
not considered hazardous for transport. Containers should
be secured against falling.
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Exposure controls / personal protection
Stability and reactivity
Danger other than fire: None known
Chemical reaction with water: No changes upon reaction with water.
Dust explosion: Compound has been tested as a combustible dust, with a class
ST-1 explosion strength (ASTME 1226 Method). As with any
organic material, a suspended dust cloud of this compound
may ignite if subject to strong ignition source or static
electricity.
Dust explosion determined by test: Y
Disposal considerations
Industry - Possibility of recovery/recycling: Trace quantities are destroyed by biological oxidation in
waste water treatment plant, larger quantities are destroyed
by incineration. No practical means of recovery or
recycling are known.
Industry - Possibility of neutralisation: SQ 28,355 is totally consumed in the drug synthesis reaction
in which it is employed. Significant residue levels in
reactor effluent are not expected. No method of chemical
neutralisation is known.
Industry - Possibility of destruction: controlled discharge: Recommended only for small quantities in accordance with
local regulations.
Industry - Possibility of destruction - incineration: Incineration is recommended for larger quantities. A
closed-cycle incinerator with scrubbers should be employed.
National regulations must be observed.
Method A:663
Industry - Possibility of destruction - water purification: Biological oxidation occurs at waste water treatment plant.
Industry - Possibility of destruction - other: None.
Public at large - Possibility of recovery/recycling: SQ 28,355 will not be available to the public at large, as
it is totally consumed in a drug synthesis reaction.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
