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EC number: 412-060-9 | CAS number: 136210-32-7 DESMOPHEN VP-LS 2973 E; DESMOPHEN VP-LS 2975 E; DESMOPHEN VP-LS 2985 E
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
Additional information
Stability (hydrolysis):
The stability of aspartic acid, N,N'-[methylenebis(2-methyl-4,1-cyclohexanediyl)]bis-, 1,1',4,4'-tetraethyl ester towards hydrolysis was determined according to the OECD-guideline 111 (Bayer Industry Services, 2006). Based on kinetic parameters, the following dissipation half-lives for a temperature of 25 °C were extrapolated based on the Arrhenius equation:
pH 4 (25 °C): t1/2: 655 h
pH 7 (25 °C): t1/2: 25.4 h
pH 9 (25 °C): t 1/2: 16.8 h
Bis-aspartic-mono-acid triethyl ester, bis-aspartic-di-acid diethyl ester, bis-aspartic-tri-acid monoethyl ester and bis-aspartic-tetra-acid of aspartic acid, N,N'-[methylenebis(2 -methyl-4,1-cyclohexanediyl)]bis-,1,1',4,4'-tetraethyl ester were determined as hydrolysis products by means of an HPLC-MS method.
Biodegradation (in water, screening test):
Aspartic acid, N,N'-[methylenebis(2-methyl-4,1-cyclohexanediyl)]bis-, 1,1',4,4'-tetraethyl ester is neither readily, nor inherently biodegradable (Bayer AG, 1998a; Currenta, 2009a)
Adsorption / desorption:
The potential of aspartic acid, N,N'-[methylenebis(2-methyl-4,1-cyclohexanediyl)]bis-,1,1',4,4'-tetraethyl ester to sorb on soil or sediment was determined according to EU-Method C.19 (HPLC-Method) yielding a logKoc between 4.2 and 5.1 (Bayer AG, 2003). The sorption coefficient was determined at pH 6 and pH 8 showing that the sorption behaviour does not depend on the prevailing pH.
According to the classification of Swann et al. (1983), aspartic acid, N,N'-[methylenebis(2 -methyl-4,1-cyclohexanediyl)]bis-,1,1',4,4'-tetraethyl ester has a high potential to sorb on soil.
Henry's Law constant
Aspartic acid, N,N'-[methylenebis(2-methyl-4,1-cyclohexanediyl)]bis-, 1,1',4,4'-tetraethyl ester is characterised by a calculated Henry Law Constant of 0.24 Pa*m³/mol (Currenta, 2009b). According to Thomas, cited in the "Handbook of Chemical property Estimation Methods" (Lyman, 1980), the substance tends to partition in water and volatilisation rates are controlled by the slow diffusion through the air. Therefore, the substance has to be scored as being slightly volatile from water.
Bioaccumulation:
A study to investigate the potential of aspartic acid, N,N'-[methylenebis(2-methyl-4,1-cyclohexanediyl)]bis-, 1,1',4,4'-tetraethyl ester to accumulate in fish yielded an uptake efficiency of 0.25 % (Currenta, 2010a). The study clearly shows that the test item has no significant potential for bioaccumulation.
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