Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 214-729-9 | CAS number: 1191-15-7
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Key value for chemical safety assessment
Genetic toxicity in vitro
Description of key information
The substance is pyrophoric, water reactive and corrosive
Link to relevant study records
- Endpoint:
- in vitro gene mutation study in bacteria
- Data waiving:
- study technically not feasible
- Justification for data waiving:
- other:
- Conclusions:
- Corrosive. Flammable in air at room temperature. Thus, exposure of bacteria in an in vitro mutagenicity test to aluminum alkyls would not generate meaningful data, and no mutagenicity study is required for this substance.
- Executive summary:
Corrosive. Flammable in air at room temperature. Thus, exposure of bacteria in an in vitro mutagenicity test to aluminum alkyls would not generate meaningful data, and no mutagenicity study is required for this substance.
Reference
Additional information
Corrosive. Flammable in air at room temperature.
Most of the chemistry of organoaluminum compounds can be explained in terms of the Lewis acidity of organoaluminum monomers, directly related to the tendency of the aluminum atom to build up an octet of electrons. Reactions of these substances are explosive. The alkyl aluminums are highly reactive towards oxidizing agents including molecular oxygen, thus, the fast reactions in air.
Reactions with Oxygen (air) - this reaction is vigorous and will generally cause the material to ignite resulting in a fire difficult to extinguish.
Reactions with Water - this reaction is even more violent than those with oxygen. The reaction causes flammable gases that are easily ignited by the fire already created by the organoaluminum compound with water.
Thus, exposure of bacteria in an in vitro mutagenicity test to aluminum alkyls would not generate meaningful data, and no mutagenicity study is required for this substance.
Short description of key information:
Corrosive. Flammable in air at room temperature. According to the Annex VII Standard Information Requirements for REACH, an in vitro gene mutation study in bacteria is required. A specific rule for adaptation for not conducting this test is not stated. However, there are mitigating circumstances as to why this test cannot be conducted.
Aluminum alkyls are highly reactive substances both towards oxygen (air) and water. They are well known to cause burns to skin and eyes, and are flammable in air and water. This fact is reflected in their EU Classification and Labelling as they are classified/labelled with symbols (F-C) and with risk-phrases ( R14-17-34 (minimum)). Thus, this test is technically not feasible to conduct and is scientifically unjustified.
Justification for classification or non-classification
Corrosive. Flammable in air at room temperature. According to the Annex VII Standard Information Requirements for REACH, an in vitro gene mutation study in bacteria is required. A specific rule for adaptation for not conducting this test is not stated. However, there are mitigating circumstances as to why this test cannot be conducted. Aluminum alkyls are highly reactive substances both towards oxygen (air) and water. They are well known to cause burns to skin and eyes, and are flammable in air and water. This fact is reflected in their EU Classification and Labelling as they are classified/labelled with symbols (F-C) and with risk-phrases ( R14-17-34 (minimum)).Thus, this test is technically not feasible to conduct and is scientifically unjustified.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.