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EC number: 201-321-0 | CAS number: 81-07-2
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
Additional information
Biodegradation:
The ready biodegradability study results (UERL) on the close read-across (sodium saccharin) indicates that the substance is moderately biodegradable. Further this is supported by the ultimate biodegradation estimate in the Biowin model (EPI suite version 4.1) shows that the current compound is moderately biodegradable (biowin 2=0.6, biowin 3=2.8, biowin<0.5).
The summary of the results are presented below
Sr.No |
Test Type |
Percentage Degradation |
Half - Life |
Parameter |
Sources |
1 |
Ready biodegradability |
50% degradation |
15 days |
Half-life |
Predicted data from PBT profiler |
2 |
Ready biodegradability |
58.2714 % degradation |
- |
O2 consumption |
Predicted data from QSAR |
By applying weight of evidence approach to the target chemical 1,2-benzisothiazol-3(2H)-one 1,1-dioxide it was found that the degradation percentage of 1,2-benzisothiazol-3(2H)-one 1,1-dioxide in water medium is 50 to 58%.This result in ready biodegradability of the chemical.
Biodegradation in water and sediment
No. of studies reviewed for Biodegradation in water and sediment from reliable sources having Klimisch rating 2.
The summary of the results are presented below
Sr.No |
Endpoint |
Percentage Degradation |
Half - Life |
Parameter |
Sources |
1. |
Ready biodegradability |
90% degradation |
Sediment-7 days |
Test material analysis |
Experimental data from Environmental Science & Technology;2014 |
2. |
Ready biodegradability |
50% degradation |
Water-15 days
Sediment-140 days |
Half-life |
Predicted data from PBT profiler |
3. |
Ready biodegradability |
50% degradation |
Water-15 days
Sediment-135 days |
O2 consumption |
Predicted data from EPI suite |
By applying weight of evidence approach to the target chemical 1,2-benzisothiazol-3(2H)-one 1,1-dioxide it was found that the degradation percentage of 1,2-benzisothiazol-3(2H)-one 1,1-dioxide in water and sediment medium in the range 50 to 90%.This result in ready biodegradability of the chemical.
Biodegradation in soil
No. of studies reviewed for Biodegradation in soil from reliable sources having Klimisch rating 2.
The summary of the results are presented below
Sr.No |
Endpoint |
Half life |
Parameter |
Result |
Sources |
1 |
Biodegradation in soil |
30 days |
Half-life |
Not persistent (Readily biodegradable) |
Predicted data from PBT profiler and EPI suite |
2 |
Biodegradation in soil |
30.2 days |
DT50(Dissipation time) |
Not persistent (Readily biodegradable) |
Predicted data from QSAR |
By applying weight of evidence approach to the target chemical,thedegradation of parent compound 1,2-benzisothiazol-3(2H)-one 1,1-dioxide in soil was estimated as 50 percent in 30 to 30.2 days whichdoes not exceeds the EPA criteria of >= 2 months (and <= 6 months). Therefore, 1,2-benzisothiazol-3(2H)-one 1,1-dioxide is estimated not to be persistent in the soil environment.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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