Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 931-740-0 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
Additional information
The substance distillation residue, butyl alcohols production, rectification is a UVCB-substance composing of several not easily identifiable substances. Only one of the constituent, 2-ethylhexanol, can be analytically quantified (typical concentration range 20 -30 %). Due to the complex composition of the substance there are a lot of technical difficulties related to the testing. The bioaccumulation depends on the physical-chemical properties of individual components in the mixture. The different constituents have different physical chemical properties (e.g. solubility, vapour pressure, octanol/water partition coefficient) that might have an effect on the overall bioaccumulation of the substance.
Because the composition of the substance is not easily identifiable, application of read-across in order to evaluate the overall bioaccumulation was regarded as an unsuitable method. The need for further investigations of the substance bioaccumulation was evaluated based on the experimental data on physical-chemical properties performed for the substance ((1) water solubility, (2) vapour pressure, (3) Kow partition coefficient and (4) hydrolysis). In addition, (5) ready biodegradation screening test results in water, and (6) aquatic toxicity data were used to evaluate the bioaccumulation.
1) According to water solubility measurements, the substance is water soluble (1.8-9 g/L) but most probably also contains constituents having low solubility in water. Because the water solubility of the constituents differs it might be difficult to maintain exposure concentrations during the BCF testing. Therefore, the BCF test (e.g. OECD 305) might not provide reliable results and testing was considered technically unfeasible.
2) Based on the experimental data, the substance is non volatile at room temperature and volatile at temperature 35 degrees Celsius (7.9 kPa) and 50 degrees Celsius (19.4 kPa).
3) Based on the experimental data on the octanol-water partition coefficient study (EC 444/2008), the substance might contain substances having potential for bioaccumulation. For complex mixtures (e.g. UVCBs) a single value of Kowwill not be definitive. Therefore, a range of values were given and the study was conducted using the HPLC method. The results of the substance indicated peaks corresponding the constituents having log Kowvalues of 1.8 to 5.8, but also constituents corresponding the log Kowvalues of 6.4 up to 7.5. However, because of the complex and unknown composition, it was not possible to evaluate which were the minor constituents and which were the major constituents representing the measured log Kowvalues.The range of log Kowvalues indicated that there might be constituents present in the mixture having potential for bioaccumulation (log Kowvalues > 3).
4) The substance is hydrolytically stable and the half-life estimated by the preliminary study (OECD 111) at three pH-values is over one year.
5) Based on the biodegradation screening test results in water, the substance was inherently biodegradable in water (OECD 301B). Some biodegradation occurred (biodeg-% 49.6) but the criteria for ready biodegradability was not fulfilled (failing 10 day-window). As a conclusion, the substance might contain more easily biodegradable substances but also constituents that are not readily biodegradable in water. These properties also indicated difficulties that may occur during BCF testing.
6) The substance was not an inhibitory to activated sludge microorganisms at maximum test concentration of 100 mg/L.
Because testing of BCF on fish was considered technically unfeasible the chemical safety assessment leans on the above existing experimental data of the substance. The experimental data on the substance indicates that the substance might contain constituents that have a potential for bioaccumulation. In conclusion, the possibility of the substance having potential for bioaccumulation cannot be neglected when considering the environmental fate and pathways of the substance.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.