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EC number: 288-003-5 | CAS number: 85631-54-5
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
In this key study the test item caused slight inhibitions on growth of the freshwater green alga Desmodesmus subspicatus after 72 hours exposure when tested with the limit concentration of 1.30 mg/L.
The nominal NOEC for inhibition of growth rate and yield after 72 hours was < 1.30 mg/L. The nominal EC50-values for inhibition of growth rate and yield were > 1.30 mg/L. For further EC-values. All effect levels are given based on the nominal concentration of Fluowet AC 812 solid, which was analytically verified via GC-MS.
Both supporting studies show that there is no toxic effects up to the water solubility.
Key value for chemical safety assessment
Additional information
Key study:
The toxicity of the test itemto the unicellular freshwater green algaDesmodesmus subspicatuswas determined according to the principles of OECD 201atDr.U.Noack-Laboratorienin 31157 Sarstedt, Germanyfrom 2013-01-22 to 2013-02-16, with the definite exposure phase from2013-02-12 to 2013-02-15.The aim of the study was to assess the effects on growth rate and yield over a period of 72 hours in a limit test.
The study was conducted under static conditions with an initial cell density of 4332 cells/mL.Based on the results of a preliminary range finding test the limit concentration of 1.30 mg/L was tested, using methanol as solvent. Therefore, a solvent control containing dilution water spiked with 0.100 mL Methanol/L was tested additionally. The nominal loading of 1.30 mg/L corresponds to the maximum solubility level of the main component C8-Perfluoroalkyl-ethylacrylate (water solubility: 0.7 mg/L, nominal content: 54.0 %). Six replicates were tested for the limit concentration, the solvent control and the control, respectively.With regard to the volatility of the test item, glass flasks without headspace were used to reduce the losses of the test item via the surface. Environmental conditionswere within the acceptable limits.
The limit concentration, the solvent control and the control were analysed by GC-MS after 0 hours (fresh media) and 72 hours (old media). The measured concentration of the main component C8-Perfluoroalkylethylacrylate of FluowetAC 812 solid(content 54.0 %) at test startwas 100 %of the nominal value. At the end of the testthe main componentgave measured concentration of 87 % of the nominal value. For details of the analytical results. All effect values are given based on the nominal concentration of the test item.
NOEC, LOEC, EC - Values of FluowetAC 812 solid(0 - 72 hours)
based on nominal test item concentration [mg/L]
Growth Rate Inhibition |
|
NOEC |
1.30 |
LOEC |
1.30 |
ErC10 |
1.30 |
ErC20 |
> 1.30 |
ErC50 |
> 1.30 |
Inhibition of Yield |
|
NOEC |
1.30 |
LOEC |
1.30 |
EyC10 |
1.30 |
EyC20 |
1.30 |
EyC50 |
> 1.30 |
The study (SSO84111) was conducted under static conditions over a duration of 72 hours with an initial cell density of 104cells/mL and a saturated solution as limit concentration, containing 0.20 mg/L. For the preparation of the saturated solution a suspension with a nominal loading of 100 mg/L was shaken for 96 hours and centrifuged. The clear supernatant was used for the test.
The test vessels were coated with the test item for 14 days before the test started. Three replicates were tested for the limit concentration and six replicates for the control. The test item was clearly dissolved throughout the test. Microscopic evaluation of the cells at study start and end of the incubation period revealed no morphological abnormalities. Water quality parameters of pH-value, measured at 0 and 72 hours, and room temperature, measured continuously, were deemed to be within acceptable limits.
The initial measured concentration of the saturated solution was 0.20 mg/L. At the end of the test the concentration of the test item was below the detection limit of 0.009 mg/L. Sorption to the glass walls of the test vessels was unlikely as the walls were already pre-coated for 14 days prior to study start.
The 72-h EbC50 (inhibition of biomass growth) > 0.20 mg/L.
The 72-h ErC50 (rate related inhibition) > 0.20 mg/L.
The 72-h NOEC for both endpoints = 0.20 mg/L.
The 72-h LOEC for both endpoints was > 0.20 mg/L.
Supporting studies:
The study (SSO84112) was conducted under static conditions over a duration of 72 hours with an initial cell density of 104cells/mL and a water accomodated fraction as limit concentration, containing 0.47 mg/L. For the preparation of the water accomodated fraction a suspension with a nominal loading of 100 mg/L was shaken for 96 hours.
The test vessels were coated with the test item for 14 days before the test started. Three replicates were tested for the limit concentration and six replicates for the control. The test item was clearly dissolved throughout the test. Microscopic evaluation of the cells at study start and end of the incubation period revealed no morphological abnormalities. Water quality parameters of pH-value, measured at 0 and 72 hours, and room temperature, measured continuously, were deemed to be within acceptable limits.
The initial measured concentration of the saturated solution was 0.47 mg/L. At the end of the test the concentration of the test item was below the detection limit of 0.009 mg/L. Sorption to the glass walls of the test vessels was unlikely as the walls were already pre-coated for 14 days prior to study start.
The 72-h EbC50 (inhibition of biomass growth) > 0.47 mg/L.
The 72-h ErC50 (rate related inhibition) > 0.47 mg/L.
The 72-h LOEC for both endpoints was > 0.47 mg/L.
The 72-h NOEC for both endpoints = 0.47 mg/L.
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