Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

repeated dose toxicity: oral
other: calculation based on classification
Type of information:
calculation (if not (Q)SAR)
Migrated phrase: estimated by calculation
Adequacy of study:
key study
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: no GLP (but other Quality Assurance); software
Cross-referenceopen allclose all
Reason / purpose for cross-reference:
reference to same study
Reason / purpose for cross-reference:
reference to other study

Data source

Reference Type:
other: software

Materials and methods

Principles of method if other than guideline:
The classification criteria (as set out in EU CLP Annex I: can be used to estimate effects derived from that classification/hazard.
GLP compliance:
(other quality assurance)

Test material

Constituent 1
Reference substance name:
Residues, copper speiss acid leaching
EC Number:
EC Name:
Residues, copper speiss acid leaching
Cas Number:
Residues, copper speiss acid leaching
Details on test material:
Typical across industry as defined in IUCLID 1.2

Results and discussion

Target system / organ toxicity

Critical effects observed:
not specified

Any other information on results incl. tables


The calculated classification via rules for mixtures resulted in “Specific target organ toxicity, repeated exposure" classification shown in section 2.1.

Applicant's summary and conclusion

Study can be used to predict the repeated organ toxicity effect and to determine hazard/classification of the UVCB substance. See Section 2 for potential resulting classifications.
Executive summary:

The study provides a conservative estimate of the repeated organ toxicity effect, derived on basis of the Classification outcome by applying the rules for mixtures of a Typical (across industry).