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Diss Factsheets
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EC number: 253-568-9 | CAS number: 37609-25-9
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
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Biodegradation in water: screening tests
Administrative data
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- Study Plan Signed 21 January 1997 - Final Report emission 27 February 1997; Experimental Phase : 21 January 1997 to 19 February 1997.
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 997
- Report date:
- 1997
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 F (Ready Biodegradability: Manometric Respirometry Test)
- GLP compliance:
- yes
Test material
- Reference substance name:
- (E)-cyclohexadec-5-enone
- Cas Number:
- 35951-24-7
- Molecular formula:
- C16H28O
- IUPAC Name:
- (E)-cyclohexadec-5-enone
- Reference substance name:
- (Z)-cyclohexadec-5-enone
- Cas Number:
- 21944-95-6
- Molecular formula:
- C16H28O
- IUPAC Name:
- (Z)-cyclohexadec-5-enone
Constituent 1
Constituent 2
- Specific details on test material used for the study:
- Name (as stated in the report): Ambretone
Batch: 261997
Study design
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge, domestic (adaptation not specified)
- Details on inoculum:
- The sludge is collected in the morning, washed three times in the mineral medium (by centrifuging at 1000 g for 10 minutes, discarding the supernatant and resuspending in mineral medium) and kept aerobic until being used on the same day.
- Duration of test (contact time):
- 28 d
Initial test substance concentration
- Initial conc.:
- 100 mg/L
- Based on:
- other: nominal test substance concentration
Parameter followed for biodegradation estimation
- Parameter followed for biodegradation estimation:
- O2 consumption
Reference substance
- Reference substance:
- other: Sodium benzoate
- Remarks:
- 99% purity
Results and discussion
% Degradation
- Key result
- Parameter:
- % degradation (O2 consumption)
- Value:
- 86
- Sampling time:
- 28 d
- Details on results:
- Oxygen uptakes, as read on the SAPROMAT meters are corrected:
- by deducting the basic oxygen uptake of sludge blank samples (Flasks 2/3 and 2/4)
- proportionally to account for the differences between actual and nominal concentrations of test and reference substance
BOD5 / COD results
- Results with reference substance:
- Degradation of Sodium Benzoate exceeds 40% after 7 days and 65% after 14 days (observed 72% biodegradation on Day 7 and 83% on Day 14): the activity of the inoculum is thus verified and the test is considered valid.
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Interpretation of results:
- readily biodegradable
- Conclusions:
- Ambretone undergoes 86% biodegradation after 28 days in the test conditions. Biodegradation starts (exceeds 10%) on day 3 (11% biodegradation) and reaches 72% at the end of the 10-day window (days 3 to 13).
Thus, Ambretone should be regarded as readily biodegradable according to this test.
The curves obtained with the reference substance alone and with Ambretone + reference substance show no toxic effect of Ambretone on the micro-organism at the test concentration. - Executive summary:
The Ready Biodegradability of Ambretone was determined by the Manometric Respirometry Test according to the OECD guideline 301F.
Ambretone undergoes 86% biodegradation after 28 days in the test conditions. Biodegradation starts (exceeds 10%) on day 3 (11%) and reaches 72% at the end of the 10-day window (days 3 to 13).
Thus, Ambretone should be regarded as readily biodegradable according to this test.
At the concentration used in the test (100 mg/L), Ambretone is not inhibitory to the micro-organisms.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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