Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 236-882-0 | CAS number: 13531-52-7
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
The substance is considered to be acutely harmful to aquatic invertebrates.
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Dose descriptor:
- EC50
- Effect concentration:
- 25.9 mg/L
Additional information
The acute toxicity of N-(2-aminoethyl)-1,3-propanediamine (CAS 13531-52-7) was studied in a static test with Daphnia magna according to German Industrial Standard test guideline DIN 38412, part 11. The nominal test concentrations were 0 (control), 3.125, 6.25, 12.5, 25.0, 50.0, and 100 mg/L. The study was performed without analytical monitoring, however, it is assumed that the test concentrations remained stable over the exposure period based on the substance's physico-chemical properties adn its environmental fate. The test item is completely miscible with water (measured; see IUCLID Ch. 4.8), which is a pre-requisite to the reliable preparation of the test concentrations. The Substance will be evenly distributed in the test medium. In addition, it is highly unlikely that the Substance will precipitate from the test medium. Evaporation of the test item from the test medium is not to be expected based on the low vapour pressure of 0.036 hPa (measured at 20 °C; see IUCLID Ch. 4.6) and the low Henry's Law constant (4.17E-08 Pa*m³/mol, HENRYWIN v3.20; see IUCLID Ch. 5.4.2). In addition, the Substance is ionized at the environmentally relevant pH range (pKa = 10.51; estimated; see IUCLID Ch. 4.21), which further reduces any tendency of the Substance to evaporate into the atmosphere. Finally, loss of the test item from the test medium due to adsorption to the test vessels is unlikely as the Substance has a low adsorption potential (log Kow = -1.67, measured; see IUCLID Ch. 4.7; log Koc = 0.96 at pH 5 to 8, calculated according to Franco & Trapp; see IUCLID Ch. 5.4.1). The 48h EC50 was determined to be 25.9 mg/L (result based on not pH-adjusted test solutions). The highest test concentration of 100 mg/L was tested in parallel after neutralization. The toxic effect was similar to the not-adjusted test solution (BASF AG, 1989; Study No. 1/0502/2/89-0503/89).
Based on the available information, the substance is considered to be acutely harmful to aquatic invertebrates.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.