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EC number: 214-968-9 | CAS number: 1229-55-6
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Bioaccumulation: aquatic / sediment
Administrative data
Link to relevant study record(s)
- Endpoint:
- bioaccumulation in aquatic species, other
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- data from handbook or collection of data
- Justification for type of information:
- Data is from authorative database
- Qualifier:
- according to guideline
- Guideline:
- other: Refer below principle
- Principles of method if other than guideline:
- Environmental Bioconcentration of test substance oil pink was determine in aquatic organisms using a measured log Kow of 7.5 and a recommended regression-derived equation
- GLP compliance:
- not specified
- Specific details on test material used for the study:
- - Name of test material: 1-[(2-methoxyphenyl)azo]-2-naphthol
- Molecular formula: C17 H14 N2 O2
- Molecular weight: 278.31 g/mol
- Smiles notation: c12c(\N=N\c3c(cccc3)OC)c(ccc1cccc2)O
- InChl : 1S/C17H14N2O2/c1-21-16-9-5-4-8-14(16)18-19-17-13-7-3-2-6-12(13)10-11-15(17)20/h2-11,20H,1H3/b19-18+
- Substance type: Organic
- Physical state: solid - Radiolabelling:
- not specified
- Vehicle:
- not specified
- Test organisms (species):
- not specified
- Route of exposure:
- aqueous
- Test type:
- not specified
- Water / sediment media type:
- natural water: freshwater
- Hardness:
- No data
- Test temperature:
- No data
- pH:
- No data
- Dissolved oxygen:
- No data
- TOC:
- No data
- Salinity:
- No data
- Conductivity:
- No data
- Details on test conditions:
- No data
- Nominal and measured concentrations:
- No data
- Reference substance (positive control):
- not specified
- Key result
- Type:
- BCF
- Value:
- 290 000 dimensionless
- Basis:
- whole body w.w.
- Remarks on result:
- other: BCF value indicates that bioconcentration in aquatic organisms will be an important fate process
- Validity criteria fulfilled:
- not specified
- Conclusions:
- From authorative database HSDB The BCF of oil pink i.e 1-[(2-methoxyphenyl)azo]-2-naphthol in aquatic organisms was reported as 290000 using a measured log Kow of 7.5 and a recommended regression-derived equation.
- Executive summary:
From authorative database HSDB The BCF of oil pink i.e 1-[(2-methoxyphenyl)azo]-2-naphthol in aquatic organisms was reported as 290000 using a measured log Kow of 7.5 and a recommended regression-derived equation.This BCF value indicates that bioconcentration in aquatic organisms will be an important fate process.
Reference
Description of key information
From authorative database HSDB The BCF of oil pink i.e 1-[(2-methoxyphenyl)azo]-2-naphthol in aquatic organisms was reported as 290000 using a measured log Kow of 7.5 and a recommended regression-derived equation. This BCF value indicates that bioconcentration in aquatic organisms will be an important fate process i.e chemical have concern for bioaccumulation in aquatic environment.
Key value for chemical safety assessment
- BCF (aquatic species):
- 290 000 dimensionless
Additional information
Two results including predicted data from authorative database and validated models for bioaccumulation (BCF) endpoint of target chemical 1-[(2-methoxyphenyl)azo]-2-naphthol (Cas no. 1229-55-6) were summarized as follows:
First study from authorative database HSDB; 2017 suggest The BCF of oil pink i.e 1-[(2-methoxyphenyl)azo]-2-naphthol in aquatic organisms was reported as 290000 using a measured log Kow of 7.5 and a recommended regression-derived equation. This BCF value indicates that bioconcentration in aquatic organisms will be an important fate process i.e chemical have concern for bioaccumulation in aquatic environment.
Above result assist by prediction done using Bio-concentration Factor (v12.1.0.50374) module from ACD (Advanced Chemistry Development)/I-Lab to determine Bio-concentration Factor over the entire pH scale 1-14 of the test substance 1-[(2-methoxyphenyl)azo]-2-naphthol.BCF estimated to be in the range 1066 to 3662 (dimentionless). This value indicates that the test substance 1-[(2-methoxyphenyl)azo]-2-naphthol was likely to be Bioaccumulative in aquatic organisms.
Thus based on the above information for bioaccumulation endpoint, it can be concluded that the test substance 1-[(2-methoxyphenyl)azo]-2-naphthol (Cas no. 1229-55-6)is expected to be Bioaccumulative in aquatic environment as both studies indicate the chemical 1-[(2-methoxyphenyl)azo]-2-naphthol exceed the BCF threshold of 2000.
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