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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

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Physical & Chemical properties

Stability in organic solvents and identity of relevant degradation products

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Administrative data

Link to relevant study record(s)

Reference
Endpoint:
stability in organic solvents and identity of relevant degradation products
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Experimental data is obtained from a variety of guideline studies.
Reason / purpose for cross-reference:
reference to other study
Reason / purpose for cross-reference:
reference to other study
Reason / purpose for cross-reference:
reference to other study
Qualifier:
no guideline followed
Principles of method if other than guideline:
Qualitative data on stability and solubilities in organic solvents is obtained froma variety of sources, including various guideline studies and analytical methods.
GLP compliance:
no
Test substance stable:
yes
Transformation products:
not specified

The substance is soluble and stable in acetonitrile (as determined by undertaking analytical studies), in n-octanol (as determined in n-octanol:water partition coefficient studies) and dimethyl sulphoxide (DMSO) as determined in studies of genetic toxicity.

Conclusions:
The substance was found to be stable in organic solvents such as acetonitrile, n-octanol, and dimethyl sulphoxide (DMSO).
Executive summary:

The stability of the test substance in organic solvents was determined as part of other guideline and analytical studies. In these studies, the test substance was found to be stable and soluble in acetonitrile (determined in analytical studies), in n-octanol (determined in partition coefficient study) and dimethyl sulphoxide (DMSO) (determined in genetic toxicity studies) (Sohar, 2012). Under the study conditions, the test substance is considered to be stable in organic solvents.

Description of key information

The stability of the test substance in organic sovents was determined in other guideline and analytical studies (Sohar, 2012).

Additional information

The test substance is stable in organic solvents such as acetonitrile, n-octanol, and dimethyl sulphoxide (DMSO).