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The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
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EC number: 923-418-3 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Partition coefficient
Administrative data
- Endpoint:
- partition coefficient
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: GLP study, OECD guideline
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 010
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 107 (Partition Coefficient (n-octanol / water), Shake Flask Method)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- shake-flask method to: flask method
- Remarks:
- Calculated with EPI suite KOWWIN
- Partition coefficient type:
- octanol-water
Test material
- Reference substance name:
- LCE08121
- IUPAC Name:
- LCE08121
- Details on test material:
- Test ITEM : LCE08121
Description of the product : Acetalization products between glucose and C14 alcohol
It is a co-emulsifier for oil-in-water emulsions in cosmetic formulas.
Constituent 1
Study design
- Analytical method:
- high-performance liquid chromatography
Results and discussion
Partition coefficient
- Type:
- log Pow
- Partition coefficient:
- 3.13
- Temp.:
- 20.2 °C
- pH:
- 6.5
- Details on results:
- none
Applicant's summary and conclusion
- Conclusions:
- The value of partition coefficient found for the test item LCE08121 is :
Pow = 1.34 E+03 and Log(Pow) = 3.13 at 20.2°C in purified water (pH 6.5). - Executive summary:
This study consisted in the determination of the partition coefficient of one batch of LCE08121 referenced as batch N° T82925.
The sdudy follow the n°107 guideline of the OECD and has been realized according to the GLP principle.
Principle of the method
The test was run according to the "Shake Flask Method" as described in EEC Method A8, in OECD guidelines for the testing of chemicals, method 107.
Outline of method
The test item is diluted into octanol saturated with water. This solution is diluted with different amounts of n-octanol saturated in water to prepare the test solutions.
After the phase separation, the concentration of the test item in the n-octanol phase (Co) and in the aqueous phase (Cw) is determined by HPLC analysis.
The partition coefficient (Pow) is calculated as the ratio between the two concentrations :
Pow= Co/Cw
Results
see test results sheet.
Conclusion
The value of partition coefficient found for the test item LCE08121 is :
Pow = 1.34 E+03 and Log(Pow) = 3.13 at 20.2°C in purified water (pH 6.5).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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