Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
skin irritation: in vitro / ex vivo
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2015
Report date:
2015

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
other: OECD 439
Deviations:
no
GLP compliance:
yes (incl. QA statement)

Test material

Constituent 1
Chemical structure
Reference substance name:
2-{phenyl[2-(tetradecanoyloxy)phenyl]methyl}phenyl tetradecanoate
EC Number:
941-526-9
Molecular formula:
C47H68O4
IUPAC Name:
2-{phenyl[2-(tetradecanoyloxy)phenyl]methyl}phenyl tetradecanoate

Results and discussion

In vitro

Results
Irritation / corrosion parameter:
other: other: in vitro assay; cell viability (MTT assay)
Value:
2.484
Remarks on result:
other:
Remarks:
Time point: 42 hr. Remarks: Negative control: 2.294; positive control: 0.056. (migrated information)

In vivo

Irritant / corrosive response data:
The test item is irritating.

Applicant's summary and conclusion

Conclusions:
The test item is not irritant. The positive control showed clear irritating effects.