Registration Dossier
Registration Dossier
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EC number: 932-286-6 | CAS number: -
Acute Toxicity: other routes
Administrative data
- Endpoint:
- acute toxicity: other routes
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 1959
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Limited documentation
Cross-reference
- Reason / purpose for cross-reference:
- reference to same study
Data source
Reference
- Reference Type:
- other company data
- Title:
- Unnamed
- Year:
- 1 959
- Report date:
- 1959
Materials and methods
Test guideline
- Qualifier:
- no guideline followed
- Principles of method if other than guideline:
- 3 rats have been subjected to a single intraperitoneal injection of 1.0 or 2.5 mL/kg bw of tertiar dodecylmercaptan.
- GLP compliance:
- no
- Remarks:
- GLP was not mandatory at the time of the study
- Limit test:
- no
Test material
- Reference substance name:
- 2,2,4,6,6-pentamethylheptane-4-thiol
- EC Number:
- 296-714-7
- EC Name:
- 2,2,4,6,6-pentamethylheptane-4-thiol
- Cas Number:
- 93002-38-1
- Molecular formula:
- C12H26S
- IUPAC Name:
- 2,2,4,6,6-pentamethylheptane-4-thiol
- Details on test material:
- - Name of test material (as cited in study report): TDM (tertiar dodecylmercaptan)
- Analytical purity: not reported
Constituent 1
Test animals
- Species:
- rat
- Strain:
- not specified
- Sex:
- not specified
- Details on test animals or test system and environmental conditions:
- No further data
Administration / exposure
- Route of administration:
- intraperitoneal
- Vehicle:
- other: oil
- Doses:
- 1.0 and 2.5 mL/kg bw (861 mg/ kg bw and 2152 mg/kg bw respectively, being the density = 0.8608 g/cm³)
- No. of animals per sex per dose:
- 3 (sex not specified)
- Control animals:
- other: not necessary
- Details on study design:
- Not reported
- Statistics:
- No data
Results and discussion
Effect levels
- Sex:
- not specified
- Dose descriptor:
- LD50
- Effect level:
- > 2 152 mg/kg bw
- Based on:
- test mat.
- Mortality:
- No mortality occurred
- Clinical signs:
- No clinical signs were observed after intraperitoneal administration of tertiar dodecylmercaptan
- Body weight:
- No data
- Gross pathology:
- No data
- Other findings:
- No further data
Any other information on results incl. tables
The intraperitoneal injection of 1.0 or 2.5 mL / kg (861 mg/ kg bw and 2152 mg/kg bw respectively, being the density = 0.8608 g/cm³) tertiar dodecylmercaptan to 3 rats caused no apparent signs of toxicity.
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
