Registration Dossier
Registration Dossier
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EC number: 204-550-4 | CAS number: 122-51-0
Genetic toxicity: in vitro
Administrative data
- Endpoint:
- in vitro gene mutation study in bacteria
- Remarks:
- Type of genotoxicity: gene mutation
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Study period:
- 1992
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: Secondary source (ECB); similar to OECD Guideline 471, but only with three S. typhimurium strains.
Data source
Reference
- Reference Type:
- secondary source
- Title:
- Unnamed
- Year:
- 1 992
- Report date:
- 2000
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other: Ames, B.N. et al., Mutat. Res. 31, 347-364 (1975)
- GLP compliance:
- no
- Type of assay:
- bacterial reverse mutation assay
Test material
- Reference substance name:
- Triethyl orthoformate
- EC Number:
- 204-550-4
- EC Name:
- Triethyl orthoformate
- Cas Number:
- 122-51-0
- Molecular formula:
- C7H16O3
- IUPAC Name:
- 1,1',1''-[methanetriyltris(oxy)]triethane
Constituent 1
Method
Species / strainopen allclose all
- Species / strain / cell type:
- S. typhimurium TA 100
- Species / strain / cell type:
- S. typhimurium TA 98
- Species / strain / cell type:
- S. typhimurium TA 97
- Metabolic activation:
- with and without
- Test concentrations with justification for top dose:
- 8, 40, 200, 1000 or 5000 ug/plate.
Results and discussion
Applicant's summary and conclusion
- Conclusions:
- Interpretation of results (migrated information):
negative
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