Registration Dossier
Registration Dossier
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EC number: 433-230-9 | CAS number: 1589-49-7
Skin irritation / corrosion
Administrative data
- Endpoint:
- skin irritation: in vivo
- Type of information:
- other: secondary source
- Adequacy of study:
- supporting study
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: The quality of the data is evaluable by means of a secondary source.
Data source
Reference
- Reference Type:
- secondary source
- Title:
- RTECS 3-methoxy, 1-Propanol
- Author:
- TOMES System
- Year:
- 2 011
- Bibliographic source:
- TOMES System (electronic version). Thomson Reuters, Greenwood Village, Colorado, USA. Edition 2011.
- Report date:
- 2011
Materials and methods
Test guideline
- Qualifier:
- no guideline available
- GLP compliance:
- not specified
Test material
- Reference substance name:
- 3-methoxypropan-1-ol
- EC Number:
- 433-230-9
- EC Name:
- 3-methoxypropan-1-ol
- Cas Number:
- 1589-49-7
- Molecular formula:
- C4H10O2
- IUPAC Name:
- 3-methoxypropan-1-ol
- Details on test material:
- Smile: C(CO)COC
Constituent 1
Test animals
- Species:
- rabbit
- Strain:
- not specified
Test system
- Type of coverage:
- not specified
- Preparation of test site:
- not specified
- Vehicle:
- not specified
- Controls:
- not specified
Results and discussion
In vivo
- Irritant / corrosive response data:
- Based on Open Draize Test the reaction is mild.
Any other information on results incl. tables
| Species | Dose | Test | Reaction | Source |
| rabbit | 10 mg/die | Open Draize Test | mild | TOMES System |
Applicant's summary and conclusion
- Interpretation of results:
- other: mild irritant
- Remarks:
- Criteria used for interpretation of results: EU
- Conclusions:
- According to Directive 67/548/EEC and to Regulation (EC) n. 1272/2008, the substance is classified as skin irritation 2 because the observed reaction is "mild" irritant after application on rabbit.
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