Registration Dossier
Registration Dossier
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EC number: 234-666-0 | CAS number: 12021-95-3
Endpoint summary
Administrative data
Description of key information
Key value for chemical safety assessment
Skin sensitisation
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not sensitising)
- Additional information:
- Migrated from Short description of key information:
Because the substance H2ZrF6 is a highly corrosive liquid (Skin Corr. 1A, H314: Causes severe skin burns and eye damage), no experimental studies investigating skin sensitisation are available. Further, read-across is applied from the solid salt dipotassium hexafluorozirconate (K2ZrF6), which was shown not to be sensitising in a guideline conform study according to OECD Guideline 406 (guinea pig maximisation study, Reference: Allen, D.J. (1997)). No classification for skin sensitisation is required for H2ZrF6.
Justification for selection of skin sensitisation endpoint:
Read-across to H2ZrF6 (no testing possible because of corrosivity) from non-corrosive salt dipotassium hexafluorozirconate based on structural similarities.
Justification for classification or non-classification
Because the substance H2ZrF6 is a highly corrosive liquid (Skin Corr. 1A, H314: Causes severe skin burns and eye damage), no experimental studies investigating skin sensitisation are available. Further, read-across is applied from the solid salt dipotassium hexafluorozirconate (K2ZrF6), which was shown not to be sensitising in a guideline conform study according to OECD Guideline 406 (guinea pig maximisation study, Reference: Allen, D.J. (1997)). No classification for skin sensitisation is required for H2ZrF6.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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