Registration Dossier
Registration Dossier
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EC number: 226-378-9 | CAS number: 5384-21-4
Endpoint summary
Administrative data
Description of key information
Hydrolysis:
On the basis of the results of both the studies and applying the weight of evidence approach, it can be concluded that the test chemical is not hydrolysable.
Additional information
Hydrolysis:
Two studies have been reviewed to determine the hydrolysis reaction of the test chemical. The studies are as mentioned below:
In first study it was mentioned that the compounds containing carbon, hydrogen, and oxygen, esters and epoxides are susceptible to hydrolysis under the OECD test conditions (OECD Guideline 111). For these hydrolysis reactions to occur, there must be 1) an electrophylic carbon atom which is 'attacked' by oxygen; and 2) a 'leaving group' which departs from the attacked carbon atom. The hydrolysis reaction of test chemical would occur by attack of water or OH- at C1, because this is the most electropositive carbon in this molecule due to the electron withdrawing effect of the phenolic OH group and the product of this reaction would be test chemical itself, indicating that there would be no net hydrolysis.
Therefore, test chemical would be hydrolytically stable under the conditions of the OECD test (OECD Guideline 111)
Another study was reviewed fom authoritative database (HSDB) in this the test chemical is not expected to undergo hydrolysis in the environment due to the lack of hydrolyzable functional groups which menas it is stable and not hydrolysable.
On the basis of the results of both the studies mentioned above and applying the weight of evidence approach, it can be concluded that the test chemical is not hydrolysable.
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