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EC number: 214-711-0 | CAS number: 1189-08-8
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Ecotoxicological Summary
Administrative data
Hazard for aquatic organisms
Freshwater
- Hazard assessment conclusion:
- PNEC aqua (freshwater)
- PNEC value:
- 0.092 mg/L
- Assessment factor:
- 100
- Extrapolation method:
- assessment factor
- PNEC freshwater (intermittent releases):
- 0.13 mg/L
Marine water
- Hazard assessment conclusion:
- PNEC aqua (marine water)
- PNEC value:
- 0.009 mg/L
- Assessment factor:
- 1 000
- Extrapolation method:
- assessment factor
STP
- Hazard assessment conclusion:
- PNEC STP
- PNEC value:
- 20 mg/L
- Assessment factor:
- 1
- Extrapolation method:
- assessment factor
Sediment (freshwater)
- Hazard assessment conclusion:
- PNEC sediment (freshwater)
- PNEC value:
- 1.6 mg/kg sediment dw
- Extrapolation method:
- equilibrium partitioning method
Sediment (marine water)
- Hazard assessment conclusion:
- PNEC sediment (marine water)
- PNEC value:
- 0.16 mg/kg sediment dw
- Extrapolation method:
- equilibrium partitioning method
Hazard for air
Air
- Hazard assessment conclusion:
- no hazard identified
Hazard for terrestrial organisms
Soil
- Hazard assessment conclusion:
- PNEC soil
- PNEC value:
- 0.573 mg/kg soil dw
- Extrapolation method:
- equilibrium partitioning method
Hazard for predators
Secondary poisoning
- Hazard assessment conclusion:
- no potential for bioaccumulation
Additional information
PNEC aqua (freshwater)
Freshwater aquatic toxicity studies with 1,3-BDDMA were conducted in invertebrates (chronic) and algal species. The acute toxicity study with fish is currently being conducted. Additional acute fish toxicity was calculated based on QSAR prediction. Algae were the most sensitive trophic level in acute and chronic studies.
The PNEC aqua (freshwater) was based on the EC10 of 9.19 mg/L determined in an algal toxicity study with Desmodesmus subspicatus.
Two chronic study results are available for this substance, which cover two trophic levels (algae and invertebrates). Fish chronic data are not available. Therefore an assessment factor of 100 was applied to the EC10 (algae) to calculate the PNEC aqua (freshwater) in accordance with Guidance on information requirements and chemical safety assessment, Chapter R.10: Characterisation of dose [concentration]-response for environment, 2008.
PNEC aqua (marine)
No tests with marine species are available. The PNEC aqua (marine) was based on the EC10 of 9.19 mg/L determined in an algal toxicity study with Desmodesmus subspicatus. An assessment factor of 1000 was applied to the EC10 to calculate the PNEC aqua (marine) in accordance with Guidance on information requirements and chemical safety assessment, Chapter R.10: Characterisation of dose [concentration]-response for environment, 2008.
PNEC aqua (intermittent release)
The PNEC aqua (intermittent release) was based on the lowest acute toxicity value of 13.0 mg/L for Desmodesmus subspicatus (72 h EC50). Based on the available data set, an assessment factor of 100 was applied to the lowest EC50 to calculate the PNEC aqua (intermittent release) in accordance with Guidance on information requirements and chemical safety assessment, Chapter R.10: Characterisation of dose [concentration]-response for environment, 2008.
PNEC STP
PNEC STP was derived using an assessment factor of 1 applied to the test concentration at which no toxicity to the inoculum was observed in the toxicity control of the ready biodegradation tests (20 mg/L) and in read across with 1,3 -BDDMA tested in a Bringman Kühn test with pseudomonas putida at a concentration of 51.2 g/l which is above the water solubilty of the substance. Additionally, in a valid OECD guideline 301B biodegradation test including a toxicity control 47.4 mg/L of the test substance 1,3-BDDMA did not inhibit microbial activity.
PNEC sediment (freshwater, marine)
No toxicity data for sediment dwelling organisms are available. Thus, the PNEC for freshwater as well as marine sediment has been calculated with the equilibrium partitioning method using EUSES 2.1.
The following data have been taken into account for the calculation:
Molecular weight [g/mol] | 226.27 |
Melting point [°C] | -23.00 |
Boiling point [°C] |
|
Vapour pressure [hPa], 20°C | 0.001 |
Water solubility [mg/L], 20°C | 243 |
Log Kow | 3.10 |
Koc (Kow method) | 322.6 |
PNEC aqua, freshwater[mg/L] | 0.087 |
PNEC aqua, marine [mg/L] | 0.0087 |
PNEC soil
No toxicity data for soil organisms are available. Thus, the PNEC for freshwater as well as marine sediment has been calculated with the equilibrium partitioning method using EUSES 2.1.
The following data have been taken into account for the calculation:
Molecular weight [g/mol] | 226.27 |
Melting point [°C] | -23.00 |
Boiling point [°C] |
|
Vapour pressure [hPa], 20°C | 0.001 |
Water solubility [mg/L], 20°C | 243 |
Log Kow | 3.10 |
Koc (Kow method) | 322.6 |
PNEC aqua, freshwater[mg/L] | 0.087 |
PNEC oral
A PNEC oral was not calculated for 1,3-BDDMA since the substance is readily biodegradable. The probability of being rapidly metabolised in exposed organisms is high. Together with the reported log Kow was 3.1 this indicates that there would be only little biomagnification of the test substance in the food chain.
Conclusion on classification
Based on the available reliable and relevant data, short-term toxicity values (L(E)C50) for daphnia and algae are >1 mg/L. 1,3-BDDMA does not need to be classified for acute toxicity to aquatic organisms according to EC No 1272/2008.
The OECD 203 short term-fish is currently being conducted.
Based on the available reliable and relevant data, long-term toxicity values (EC10) for aquatic invertebrates and algae are > 1 mg/L, and 1,3-BDDMA is readily biodegradable. Thus, 1,3-BDDMA does not need to be classified for chronic toxicity to aquatic organisms according to Regulation EC No 1272/2008.
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