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EC number: 232-576-6 | CAS number: 9001-03-0
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
GLP Daphnia study as selected as read-across from Xanthan lyase. Non-GLP studies are available on Carbonic anhydrase as a supporting studies.
Exposure of Daphnia magna to Xanthan lyase, batch PPE55581 gave EC50 value of greater than 1761.4 mg enzyme concentrate dry matter/L (equivalent to 100 mg aep/L). The No Observed Effect Concentration (NOEC) was the highest concentration tested, 1761.4 mg enzyme concentrate dry matter/L (equivalent to 100 mg aep/L).
Exposure of Daphnia magna to Carbonic anhydraase, batch PPE93985 has been investigated based on nominal concentrations revealed no effect on immobilization. The 48-hour EC50 value was greater than the highest concentration tested 676.6 mg enzyme concentrate dry matter/L (equivalent to 100 mg active enzyme protein/L). The NOEC is 676.6 mg enzyme concentrate dry matter/L (equivalent to 100 mg active enzyme protein/L).
The exposure of R. subcapitata to Carbonic anhydrase, batch PPE93985 was toxic to algae based on its algaestatic, CO2 quenching mode of action. 250 mg sodium bicarbonate and constant shaking were introduced to the test system. 72-hr EC50 was 59.4 mg enzyme concentrate dry matter, equivalent to 8.8 mg active enzyme protein/L. The study is non-GLP and analytical measurements have not been undertaken.
Additional information
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