Registration Dossier
Registration Dossier
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EC number: 610-200-5 | CAS number: 446292-07-5
Water solubility
Administrative data
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2007
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 007
- Report date:
- 2007
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.6 (Water Solubility)
- Deviations:
- no
- GLP compliance:
- yes
- Type of method:
- flask method
Test material
- Reference substance name:
- 1H-Isoindole-1,3(2H)-dione, 2-[(2R)-2-hydroxy-3-[[4-(3-oxo-4-morpholinyl)phenyl]amino]propyl]-
- IUPAC Name:
- 1H-Isoindole-1,3(2H)-dione, 2-[(2R)-2-hydroxy-3-[[4-(3-oxo-4-morpholinyl)phenyl]amino]propyl]-
- Reference substance name:
- 2-[(2R)-2-hydroxy-3-{[4-(3-oxomorpholin-4-yl)phenyl]amino}propyl]-1H-isoindole-1,3(2H)-dione
- EC Number:
- 610-200-5
- Cas Number:
- 446292-07-5
- Molecular formula:
- C21 H21 N3 O5
- IUPAC Name:
- 2-[(2R)-2-hydroxy-3-{[4-(3-oxomorpholin-4-yl)phenyl]amino}propyl]-1H-isoindole-1,3(2H)-dione
Constituent 1
Constituent 2
Results and discussion
Water solubilityopen allclose all
- Key result
- Water solubility:
- 0.036 g/L
- Temp.:
- 20 °C
- pH:
- 6.3
- Key result
- Water solubility:
- 0.038 g/L
- Temp.:
- 20 °C
- pH:
- 6.4
- Key result
- Water solubility:
- 0.036 g/L
- Temp.:
- 20 °C
- pH:
- 6.4
- Details on results:
- The mean value of the different flasks is: 0.037 g/L at 20°C. Result of the preliminary test: 0.031 g/L.
Applicant's summary and conclusion
- Conclusions:
- The mean value of the water solubility of Hydroxyaminophthalimid is 0.037 g/L.
- Executive summary:
The mean value of the water solubility of Hydroxyaminophthalimid is 0.037 g/L (Bayer Study, 2007).
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