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Diss Factsheets
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EC number: 429-100-6 | CAS number: 23911-56-0
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 1997-11-07 to 1997-12-05
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- EU Method C.4-E (Determination of the "Ready" Biodegradability - Closed Bottle Test)
- Version / remarks:
- 1992
- Deviations:
- no
- GLP compliance:
- yes
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge, domestic, non-adapted
- Details on inoculum:
- - Type: mixed population of aquatic microorganisms (activated sludge)
- Origin: effluent of laboratory scale unit receiving sewage from the Wupper area water authority (predominantly domestic sewage). - Duration of test (contact time):
- 28 d
- Initial conc.:
- 3 mg/L
- Based on:
- test mat.
- Parameter followed for biodegradation estimation:
- O2 consumption
- Details on study design:
- TEST CONDITIONS
- Test temperature: 20 +/- 1 °C
- pH adjusted: yes
- Continuous darkness: yes
TEST SYSTEM
- Culturing apparatus: Glass bottle
- Number of culture flasks/concentration: 10 bottles
SAMPLING
- Sampling frequency: 7 day
CONTROL AND BLANK SYSTEM
- Inoculum blank: 10 bottles
- Process control: 10 bottles (Aniline)
- Toxicity control: 10 bottles (Aniline + test item) - Reference substance:
- aniline
- Key result
- Parameter:
- % degradation (O2 consumption)
- Value:
- 4
- Sampling time:
- 28 d
- Results with reference substance:
- 80% degradation within 14 days
- Validity criteria fulfilled:
- yes
- Interpretation of results:
- not readily biodegradable
- Conclusions:
- The test item was not readily biodegradable (4% based on O2 consumption) under the chosen test conditions.
- Executive summary:
The ready biodegradability of the test item was tested according to council directive 92/69 EEC method C.4-E and GLP. The test item at a concentration of 3 mg was inoculated with 5 ml/L sewage effluent in closed glass bottles 28 d. The degradation process was followed by weekly measurements of the BOD in the aqueous phase. Degradation was expressed as BOD to ThOD in %. After 28 d, the average degradation rate of the test item was 4%, therefore, the test item was considered as not readily biodegradable. The degradation of the reference substance aniline reached 80% within 14 days, thus confirming the suitability of the inoculum.
Reference
Dissolved oxygen of blank inoculum (mg O2/L after x day):
Bottle No. | 0 days | Bottle No. | 7 days | Bottle No. | 14 days | Bottle No. | 21 days | Bottle No. | 28 days |
1 | 8.83 | 3 | 8.56 | 5 | 8.55 | 7 | 8.55 | 9 | 8.54 |
2 | 8.83 | 4 | 8.62 | 6 | 8.63 | 8 | 8.59 | 10 | 8.62 |
Mean | 8.83 | Mean | 8.59 | Mean | 8.59 | Mean | 8.57 | Mean | 8.58 |
Dissolved oxygen of reference substance (mg O2/L after x day):
Bottle No. | 0 days | Bottle No. | 7 days | Bottle No. | 14 days | Bottle No. | 21 days | Bottle No. | 28 days |
11 | 8.87 | 13 | 5.86 | 15 | 4.83 | 17 | 4.67 | 19 | 4.34 |
12 | 9.01 | 14 | 5.4 | 16 | 4.93 | 18 | 4.63 | 20 | 4.44 |
Mean | 8.94 | Mean | 5.63 | Mean | 4.88 | Mean | 4.65 | Mean | 4.39 |
Dissolved oxygen of test substance (mg O2/L after x day):
Bottle No. | 0 days | Bottle No. | 7 days | Bottle No. | 14 days | Bottle No. | 21 days | Bottle No. | 28 days |
21 | 8.98 | 23 | 8.54 | 25 | 8.59 | 27 | 8.53 | 29 | 8.34 |
22 | 8.97 | 24 | 8.68 | 26 | 8.62 | 28 | 8.56 | 30 | 8.47 |
Mean | 8.98 | Mean | 8.61 | Mean | 8.61 | Mean | 8.55 | Mean | 8.46 |
Dissolved oxygen of toxicity control (mg O2/L after x day):
Bottle No. | 0 days | Bottle No. | 7 days | Bottle No. | 14 days | Bottle No. | 21 days | Bottle No. | 28 days |
31 | 8.98 | 33 | 5.57 | 35 | 4.49 | 37 | 4.35 | 39 | 4.04 |
32 | 8.97 | 34 | 5.5 | 36 | 4.76 | 38 | 4.43 | 40 | 4.22 |
Mean | 8.98 | Mean | 5.54 | Mean | 4.63 | Mean | 4.39 | Mean | 4.13 |
Results-Do depletion: % degradation
a. Testsubstance:
Test substance | DO depletion after n days | |||
7 d | 14 d | 21 d | 28 d | |
No.1: (mt0-mtx)-(mb0-mbx) | 0.2 | 0.15 | 0.19 | 0.29 |
No.2: (mt0-mtx)-(mb0-mbx) | 0.06 | 0.12 | 0.16 | 0.26 |
D1: % Degradation | 3 | 2 | 3 | 4 |
D2: % Degradation | 1 | 2 | 2 | 4 |
D, Mean | 2 | 2 | 3 | 4 |
b. Reference substance
Reference substance | DO depletion after n days | |||
7 d | 14 d | 21 d | 28 d | |
No.1: (mt0-mtx)-(mb0-mbx) | 2.77 | 3.8 | 3.94 | 4.28 |
No.2: (mt0-mtx)-(mb0-mbx) | 3.37 | 3.84 | 4.12 | 4.32 |
D1: % Degradation | 57 | 79 | 82 | 89 |
D2: % Degradation | 70 | 80 | 86 | 90 |
D, Mean | 64 | 80 | 84 | 90 |
c. Toxicitx control
Toxicity Control | DO depletion after n days | |||
7 d | 14 d | 21 d | 28 d | |
No.1: (mt0-mtx)-(mb0-mbx) | 3.17 | 4.25 | 4.37 | 4.69 |
No.2: (mt0-mtx)-(mb0-mbx) | 3.23 | 3.97 | 4.28 | 4.5 |
D1: % Degradation | 27 | 36 | 37 | 40 |
D2: % Degradation | 28 | 34 | 37 | 38 |
D, Mean | 28 | 35 | 37 | 39 |
Description of key information
Key value for chemical safety assessment
- Biodegradation in water:
- under test conditions no biodegradation observed
- Type of water:
- freshwater
Additional information
The ready biodegradability of the test item was tested according to council directive 92/69 EEC method C.4-E and GLP. The test item at a concentration of 3 mg was inoculated with 5 ml/L sewage effluent in closed glass bottles 28 d. The degradation process was followed by weekly measurements of the BOD in the aqueous phase. Degradation was expressed as BOD to ThOD in %. After 28 d, the average degradation rate of the test item was 4%, therefore, the test item was considered as not readily biodegradable. The degradation of the reference substance aniline reached 80% within 14 days, thus confirming the suitability of the inoculum.
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