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EC number: 827-772-9 | CAS number: 20650-07-1
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Toxicity to microorganisms
Administrative data
- Endpoint:
- toxicity to microorganisms, other
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- study well documented, meets generally accepted scientific principles, acceptable for assessment
- Remarks:
- non-standard information included in biodegradation study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 020
- Report date:
- 2020
Materials and methods
Test guideline
- Qualifier:
- no guideline followed
- Principles of method if other than guideline:
- OECD 301F was applied (see biodegradation study summary for all methodological details), and included a toxicity control where the reference substance sodium benzoate was monitored for biodegradation based on O2 consumption, in presence of 22 mg/L DMMOPA.
- GLP compliance:
- yes (incl. QA statement)
Test material
- Reference substance name:
- (3-methoxypropyl)dimethylamine
- EC Number:
- 827-772-9
- Cas Number:
- 20650-07-1
- Molecular formula:
- C6H15NO
- IUPAC Name:
- (3-methoxypropyl)dimethylamine
Constituent 1
Test organisms
- Test organisms (species):
- activated sludge, domestic
- Details on inoculum:
- see biodegradation study summary
Study design
- Test type:
- static
- Limit test:
- yes
- Total exposure duration:
- 28 d
Test conditions
- Reference substance (positive control):
- yes
- Remarks:
- benzoic acid, sodium salt
Results and discussion
Effect concentrations
- Key result
- Duration:
- 28 d
- Dose descriptor:
- EC50
- Effect conc.:
- > 22 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- other: test material introduced at t0
- Basis for effect:
- other: inhibition of biodegradation of sodium benzoate
- Details on results:
- In the reference control, biodegradation of sodium benzoate reached 84% and 88% within 14 and 28 days of exposure, resp.
In the toxicity control with 22 mg/L DMMOPA, biodegradation of sodium benzoate reached 61% and 67% within 14 and 28 days of exposure, resp.
Therefore, the test substance had no significant inhibitory effect on the activity of the microbial inoculum. The EC50 was above 22 mg/L.
Applicant's summary and conclusion
- Validity criteria fulfilled:
- not applicable
- Remarks:
- non-standard method as a complement inside a biodegradation study
- Executive summary:
In an OECD 301F study, the reference substance sodium benzoate was readily biodegradable in the toxicity control experiment with 22 mg/L DMMOPA. Therefore, DMMOPA did not have a significant toxic or inhibitory effect on the activity of the microbial inoculum. The corresponding EC50 was > 22 mg/L over 28 days.
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