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Diss Factsheets
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EC number: 856-663-9 | CAS number: 2400970-89-8
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Water solubility
Administrative data
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Study period:
- 29 September 2020 thru 14 October 2020
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- study well documented, meets generally accepted scientific principles, acceptable for assessment
- Justification for type of information:
- Weight of Evidence assessment consisting of a non-standard testing methodology and supported by a valid QSAR model.
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 020
- Report date:
- 2020
Materials and methods
Test guideline
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- OECD Guideline 105 (Water Solubility)
- Deviations:
- yes
- Remarks:
- Antimony & Sulfur (as CS2) used as surrgate analytes
- Principles of method if other than guideline:
- The study was performed through a combination of principles established in the following test guidelines / methods:
• OECD Guidelines for Testing of Chemicals, Section 1, No. 105, "Water Solubility", adopted 27 July 1995; Shake Flask Method [OECD 1995].
• NIOSH Method 1600, Carbon Disulfide [NIOSH 1994a].
• NIOSH Method 7303, Elements by ICP (Hot Block/HCl/HNO3 Digestion) [NIOSH 2003], with Mass Spectrometry (MS) detector.
• U.S. EPA Method 630, The Determination of Dithiocarbamate Pesticides in Industrial and Municipal Wastewaters [US EPA 2002]. - GLP compliance:
- no
- Other quality assurance:
- other:
- Remarks:
- This study was performed in accordance with AIHA-LAP, LLC quality procedures and NIOSH PAT. Although not equivalent to GLP, they are sufficiently robust to assure data quality for purposes of this study.
- Type of method:
- flask method
Test material
- Reference substance name:
- Carbamodithioic acid, bis(mixed 2-ethylhexyl and 2-methylbutyl and pentyl) derivs., antimony (3+) salts
- Molecular formula:
- C33H66N3S6Sb to C51H102N3S6Sb
- IUPAC Name:
- Carbamodithioic acid, bis(mixed 2-ethylhexyl and 2-methylbutyl and pentyl) derivs., antimony (3+) salts
- Test material form:
- liquid: viscous
Constituent 1
- Specific details on test material used for the study:
- PYSICAL DESCRIPTION: Highly viscous amber liquid.
PURITY: >99%
SOURCE OF TEST MATERIAL
- Source and lot/batch number of test material: WT05-19
- Expiration date of the lot/batch: not applicable
STABILITY AND STORAGE CONDITIONS OF TEST MATERIAL
- Storage condition of test material: room temp.
- Stability under storage conditions: stable for the duration of testing.
Results and discussion
Water solubility
- Key result
- Water solubility:
- <= 0.6 mg/L
- Conc. based on:
- element (dissolved fraction)
- Remarks:
- solubility of parent compound likely far lower
- Loading of aqueous phase:
- 1.73 mg/L
- Incubation duration:
- 4 h
- Temp.:
- 30 °C
- pH:
- > 6 - < 8
- Details on results:
- The solubility of the test item in water is ≤ 0.6 mg/l, likely not as the parent compound but rather soluble antimony compounds and other possible degredation products.
Any other information on results incl. tables
Mass of test item introduced into 1 Liter of water: 1.73 mg (= 246 µg Sb)
Mass of antimony (Sb) recovered via filtration: 110 µg
Mass of Sb not recovered via filtration: 136 µg
Final volume of test solution: 1.5 L
Conversion factor from Sb to test item: 0.142
Soluble portion of test item: 0.136 mg ÷ 1.5 L ÷ 0.134 = 0.6 mg/L
Sb Positive Control Sample (Expected vs. Actual): 190 µg vs. 189 µg (0.53% difference) indicating the solubility portion of the study performed as expected.
CS2 Positive Control Sample (Expected vs. Actual): 367 µg vs. < 6 µg indicating the test item may not decompose in water to form CS2.
Applicant's summary and conclusion
- Conclusions:
- The solubility of the test item in water is ≤ 0.6 mg/l, likely not as the parent compound but rather soluble antimony compounds and other possible degredation products.
- Executive summary:
In a study conducted in accordance with the main principles of OECD Guideline Method 105 under robust quality procedures similar to those required under GLP, the test item was determined to have a water solubility ≤ 0.6 mg/l, likely not as the parent compound but rather soluble antimony compounds and other possible degredation products.
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