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Physical & Chemical properties

Vapour pressure

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Reference
Endpoint:
vapour pressure
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2020-06-10 to 2020-06-20
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
OECD Guideline 104 (Vapour Pressure Curve)
Version / remarks:
2006
Deviations:
no
Qualifier:
according to guideline
Guideline:
EU Method A.4 (Vapour Pressure)
Version / remarks:
2009
Deviations:
no
GLP compliance:
yes (incl. QA statement)
Type of method:
effusion method: Knudsen cell
Test no.:
#1
Temp.:
20 °C
Vapour pressure:
0 Pa
Key result
Test no.:
#2
Temp.:
25 °C
Vapour pressure:
0 Pa

Temperature, °C

Δm/Δt, mg/min

Vapour pressure, Pa

90.0

1.4727 x 10-5

3.0768 x 10-3

100.0

2.7070 x 10-5

5.7329 x 10-3

110.0

1.5960 x 10-4

3.4251 x 10-2

120.0

6.7927 x 10-4

1.4766 x 10-1

130.0

2.2261 x 10-3

4.9002 x 10-1

140.0

5.2124 x 10-3

1.1615

150.0

8.3642 x 10-3

1.8863

 

For the evaluation the measured vapour pressure values were plotted against the inverse temperature. The linear regression lead to following results.

Intercept

Slope

R. Squared

18.8488

-7784.3730

0.9822

 

The vapour pressures at 20 and 25 °C were calculated by extrapolation to be1.971 x 10-8Pa and 5.494 x 10-8Pa, respectively.

Conclusions:
The mean vapour pressure of the test item was found to be and 5.494 x 10-8 Pa at 25 °C.
Executive summary:

The vapour pressure of the test item was determined using theKnudsen Effusion Methodaccording to Regulation (EC) No. 440/2008 Method A.4. Vapour pressure and OECD Test Guideline 104 (2006). The vapour pressure between 90 and 150 °C was plottedagainst the inverse temperature. The vapour pressures at 20 and 25 °C were calculated by extrapolation to be1.971 x 10-8 Pa and 5.494 x 10-8 Pa, respectively.

Description of key information

The mean vapour pressure of the test item was found to be 5.494 x 10-8 Pa at 25 °C (reference 4.6 -1).

Key value for chemical safety assessment

Vapour pressure:
0 Pa
at the temperature of:
25 °C

Additional information

The vapour pressure of the test item was determined using the Knudsen Effusion Method according to Regulation (EC) No. 440/2008 Method A.4. Vapour pressure and OECD Test Guideline 104 (2006). The vapour pressure between 90 and 150 °C was plotted against the inverse temperature. The vapour pressures at 20 and 25 °C were calculated by extrapolation to be1.971 x 10-8 Pa and 5.494 x 10-8 Pa, respectively.