Registration Dossier

Data platform availability banner - registered substances factsheets

Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Environmental fate & pathways

Biodegradation in water: screening tests

Currently viewing:

Administrative data

Link to relevant study record(s)

Referenceopen allclose all

Endpoint:
biodegradation in water: ready biodegradability
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
OECD Guideline 301 B (Ready Biodegradability: CO2 Evolution Test)
Deviations:
no
Qualifier:
according to guideline
Guideline:
EPA OTS 796.3260 (Ready Biodegradability: Modified Sturm Test)
Deviations:
no
GLP compliance:
yes
Oxygen conditions:
aerobic
Inoculum or test system:
activated sludge, domestic (adaptation not specified)
Details on inoculum:
The concentration of suspended solids was determined to be 4.0 g/l in the concentrated sludge. Before use, the sludge was allowed to settle (35 minutes) and the supernatant liquid was used as inoculum at the amount of 10 ml/l of mineral medium.
Duration of test (contact time):
28 d
Initial conc.:
12 mg/L
Based on:
TOC
Initial conc.:
53.3 mg/L
Based on:
test mat.
Parameter followed for biodegradation estimation:
CO2 evolution
Reference substance:
acetic acid, sodium salt
Test performance:
all criteria for acceptability of the test were met
Parameter:
% degradation (CO2 evolution)
Value:
1
Sampling time:
2 d
Parameter:
% degradation (CO2 evolution)
Value:
1
Sampling time:
5 d
Parameter:
% degradation (CO2 evolution)
Value:
1
Sampling time:
7 d
Parameter:
% degradation (CO2 evolution)
Value:
1
Sampling time:
9 d
Parameter:
% degradation (CO2 evolution)
Value:
1
Sampling time:
12 d
Parameter:
% degradation (CO2 evolution)
Value:
3
Sampling time:
14 d
Parameter:
% degradation (CO2 evolution)
Value:
3
Sampling time:
19 d
Parameter:
% degradation (CO2 evolution)
Value:
3
Sampling time:
23 d
Parameter:
% degradation (CO2 evolution)
Value:
3
Sampling time:
27 d
Parameter:
% degradation (CO2 evolution)
Value:
4
Sampling time:
29 d
Validity criteria fulfilled:
yes
Interpretation of results:
not readily biodegradable
Conclusions:
Tetraethylammoniumhydroxide (TEAH) 35% in water was designated as not readily biodegradable.
Executive summary:

Desmares-Koopmans (2014) is a GLP-compliant study following OECD guideline 301B. It is reliable without restrictions and can be used as a key study for this endpoint. Tetraethylammoniumhydroxide (TEAH) 35% in water was designated as not readily biodegradable.

Endpoint:
biodegradation in water: ready biodegradability
Data waiving:
study technically not feasible
Justification for data waiving:
the study does not need to be conducted because the substance is inorganic

Description of key information

Biodegradation is not relevant for inorganic substances, but as this substance has an organic component the biodegradation potential of the organic part of the test item has been assessed. Tetraethylammoniumhydroxide (TEAH) 35% in water was designated as not readily biodegradable.

Key value for chemical safety assessment

Biodegradation in water:
under test conditions no biodegradation observed
Type of water:
freshwater

Additional information

Biodegradation is not relevant for inorganic substances, but as this substance has an organic component the biodegradation potential of the organic part of the test item has been assessed. Desmares-Koopmans (2014) is a GLP-compliant study following OECD guideline 301B. It is reliable without restrictions and can be used as a key study for this endpoint. Tetraethylammoniumhydroxide (TEAH) 35% in water was designated as not readily biodegradable.