Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 476-670-7 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- July-September 2003
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: study acc. to GLP
- Qualifier:
- according to guideline
- Guideline:
- EU Method C.4-B (Determination of the "Ready" Biodegradability - Modified OECD Screening Test)
- Version / remarks:
- in all essential parts identical with OECD Guideline 301 E
- Principles of method if other than guideline:
- The method assess the ready biodegradability of a test iteam under aerobic conditions at 22 +/- 2oC. Degradation is followed by DOC analysis at frequent intervals over a 28 day period. The degree of biodegradation is calculated by expressing the concentration of DOC removed (correccted for that in the blank inoculum control) as a percentage of the concentration initially present.
- GLP compliance:
- yes
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- sewage, domestic (adaptation not specified)
- Details on inoculum:
- Test organism:
- type: mixed population of aquatic microorganisms
- origin: secendary effluent of a domestic sewage treatment plant
- pretreatment: separation of coarse particles by filtration
- concentration of effluents in reaction mixture: 0.5 ml/L - Duration of test (contact time):
- ca. 28 d
- Initial conc.:
- ca. 20 mg/L
- Based on:
- DOC
- Parameter followed for biodegradation estimation:
- DOC removal
- Details on study design:
- The following type of flask were used:
- Test suspension (2 parallels)
A measured volume of mineral medium containing a known concentration of the test item (as the nominal sole source of organic carbon) and inoculum
- Procedure control (2 parallels)
In order to check the procedure, the reference chemical sodium benzoate is tested by setting up 2 flask in parallel to the normal tests runs.
- Inoculum blank (2 parallels)
A measured volume of mineral medium containing only inoculum
- Toxicity control (1 parallel)
Toxic effects of the test item are determined in a toxicity control flask (containing test item, reference substance and inoculum).
Each flask was inocuated with 0.5 ml effluent per litre medium. The mixtures were aerated in the dark at 22 +/- 2oC.
Degradation was followed by DOC analysis at frequent intervals over a 28 day period. The degree of biodegradation was calculated by expressing the concentration of DOC removed (correccted for that in the blank inoculum control) as a percentage of the concentration initially present. - Reference substance:
- benzoic acid, sodium salt
- Parameter:
- % degradation (DOC removal)
- Value:
- 79
- Sampling time:
- 7 d
- Parameter:
- % degradation (DOC removal)
- Value:
- 73
- Sampling time:
- 14 d
- Parameter:
- % degradation (DOC removal)
- Value:
- 74
- Sampling time:
- 21 d
- Parameter:
- % degradation (DOC removal)
- Value:
- 84
- Sampling time:
- 27 d
- Parameter:
- % degradation (DOC removal)
- Value:
- 81
- Sampling time:
- 28 d
- Details on results:
- All validity criteria of the test method were met:
- The reference compound has reached the level for ready biodegradability by 14 days
- no toxicity of the test item was observed in the toxicity control
- the difference of extremes of replicate values of the removal of test chemical at the end of the test is less than 20%.
- the DOC content of the blank control at the begining of the test is <= 5 mg/L. - Results with reference substance:
- % degradation for reference substance:
- 7 days: 100%
- 14 days: 96%
- 21 days: 99%
- 27 days: 100%
- 28 days: 100% - Validity criteria fulfilled:
- yes
- Interpretation of results:
- readily biodegradable
- Conclusions:
- Within 28 days, a degradation of 81% was determined for Fe(III)IDHA. Fe(III)IDHA has to be classified as readily biodegradable.
- Executive summary:
A study was performed to assess the ready biodegradablility of IDS Fe Komplex (Fe(III)IDHA).
The study was conducted in accordance with the Commission Directive 92/69/EEC. Method C.4 -B: Modified OECD Screening test. This test method is in all essential parts identical with OECD Guideline 301 E.
A solution of Fe(III)IDHA in a mineral medium was inoculated with secondary effluent from a domestic sewage treatment plant and incubated under aerobic conditions. Degradation was followed by DOC determinations at 0h, 7 d, 14 d, 21 d, 27 d and 28 d.
Fe(III)IDHA showed:
79% degradation after 7 days
73% degradation after 14 days
74% degradation after 21 days
84% degradation after 27 days
81% degradation after 28 days
Therefore Fe(III)IDHA has to be classified as "readily biodegradable".
The reference substance showed 96% degradation after 14 days.
Reference
Description of key information
Within 28 days, a degradation of 81% was determined for Fe(III)IDHA. Fe(III)IDHA has to be classified as readily biodegradable.
Key value for chemical safety assessment
- Biodegradation in water:
- readily biodegradable
Additional information
Biodegradability of Fe(III)IDHA was evaluated in two test:
- Method C.4 -B: Modified OECD Screening test. This test method is in all essential parts identical with OECD Guideline 301 E.
- OECD Guideline 302 B - Inherent Biodegradability. Method: Zahn-Wellens/EMPA-Test.
The both study showed good biodegradability of eveluated substance Fe(III)IDHA:
- 81% after 28 days in ready biodegradability study (OECD 301E)
- 92% after 28 days in inherent biodegradability test (OECD 302 B).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.