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EC number: 430-050-2 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water and sediment: simulation tests
Administrative data
Link to relevant study record(s)
- Endpoint:
- biodegradation in water and sediment: simulation testing, other
- Type of information:
- calculation (if not (Q)SAR)
- Adequacy of study:
- supporting study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- accepted calculation method
- Principles of method if other than guideline:
- The biodegradability is estimated by calculation from molecular fragments using the models BioWin3 and BioWin5 (BIOWIN v4.10). Criteria for the "yes" or "no" prediction: If the Biowin3 (ultimate survey model) result is "weeks" or faster (i.e. "days", "days to weeks", or "weeks" AND the Biowin5 (MITI linear model) probability is >= 0.5, then the prediction is YES (readily biodegradable). If this condition is not satisfied, the prediction is NO (not readily biodegradable). This method is based on application of Bayesian analysis to ready biodegradation data.
- GLP compliance:
- not specified
- Specific details on test material used for the study:
- CAS Number: 123-26-2SMILES : CCCCCCC(CCCCCCCCCCC(=O)NCCNC(=O)CCCCCCCCCCC(CCCCCC)O)OCHEM : 12-hydroxy-N-[2-(12-hydroxyoctadecanoylamino)ethyl]octadecanamideMOL FOR: C38 H76 N2 O4MOL WT : 625.04
- Radiolabelling:
- not specified
- Oxygen conditions:
- not specified
- Inoculum or test system:
- not specified
- Details on results:
- Biowin3 (Ultimate Biodegradation Timeframe): Weeks-MonthsBiowin5 (MITI Linear Model Prediction): Biodegrades FastReady Biodegradability Prediction: No
- Validity criteria fulfilled:
- not applicable
- Conclusions:
- From the calculations it can be expected that the test material is not readily biodegradable.
- Executive summary:
The given biodegradability of 12-hydroxy-N-[2-(12-hydroxyoctadecanoylamino)ethyl]octadecanamide is calculated from BIOWIN 4.10 using the models BioWin3 and BioWin5. From the combined results it can be concluded that the test material is not readily biodegradable. EPA recommends that EPI Suite is a screening-level tool and should not be used if acceptable measured values are available.
- Endpoint:
- biodegradation in water and sediment: simulation testing, other
- Type of information:
- calculation (if not (Q)SAR)
- Adequacy of study:
- supporting study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- accepted calculation method
- Principles of method if other than guideline:
- The biodegradability is estimated by calculation from molecular fragments using the models BioWin3 and BioWin5 (BIOWIN v4.10). Criteria for the "yes" or "no" prediction: If the Biowin3 (ultimate survey model) result is "weeks" or faster (i.e. "days", "days to weeks", or "weeks" AND the Biowin5 (MITI linear model) probability is >= 0.5, then the prediction is YES (readily biodegradable). If this condition is not satisfied, the prediction is NO (not readily biodegradable). This method is based on application of Bayesian analysis to ready biodegradation data.
- GLP compliance:
- not specified
- Specific details on test material used for the study:
- CAS Number: 146781-64-8SMILES : CCCCCCCCCC(=O)NCCNC(=O)CCCCCCCCCCC(CCCCCC)OCHEM : N-[2-(decanoylamino)ethyl]-12-hydroxyoctadecanamideMOL FOR: C30 H60 N2 O3MOL WT : 496.82
- Radiolabelling:
- not specified
- Oxygen conditions:
- not specified
- Inoculum or test system:
- not specified
- Details on results:
- Biowin3 (Ultimate Biodegradation Timeframe): Weeks-MonthsBiowin5 (MITI Linear Model Prediction): Biodegrades FastReady Biodegradability Prediction: No
- Validity criteria fulfilled:
- not applicable
- Conclusions:
- From the calculations it can be expected that the test material is not readily biodegradable.
- Executive summary:
The given biodegradability of N-[2 -(decanoylamino)ethyl]-12 -hydroxyoctadecanamidei s calculated from BIOWIN 4.10 using the models BioWin3 and BioWin5. From the combined results it can be concluded that the test material is not readily biodegradable. EPA recommends that EPI Suite is a screening-level tool and should not be used if acceptable measured values are available.
- Endpoint:
- biodegradation in water and sediment: simulation testing, other
- Type of information:
- calculation (if not (Q)SAR)
- Adequacy of study:
- supporting study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- accepted calculation method
- Principles of method if other than guideline:
- The biodegradability is estimated by calculation from molecular fragments using the models BioWin3 and BioWin5 (BIOWIN v4.10). Criteria for the "yes" or "no" prediction: If the Biowin3 (ultimate survey model) result is "weeks" or faster (i.e. "days", "days to weeks", or "weeks" AND the Biowin5 (MITI linear model) probability is >= 0.5, then the prediction is YES (readily biodegradable). If this condition is not satisfied, the prediction is NO (not readily biodegradable). This method is based on application of Bayesian analysis to ready biodegradation data.
- GLP compliance:
- not specified
- Specific details on test material used for the study:
- CAS Number: 51139-08-3SMILES : CCCCCCCCCC(=O)NCCNC(=O)CCCCCCCCCCHEM : N-[2-(decanoylamino)ethyl]decanamideMOL FOR: C22 H44 N2 O2MOL WT : 368.61
- Radiolabelling:
- not specified
- Oxygen conditions:
- not specified
- Inoculum or test system:
- not specified
- Details on results:
- Biowin3 (Ultimate Biodegradation Timeframe): WeeksBiowin5 (MITI Linear Model Prediction): Biodegrades FastReady Biodegradability Prediction: Yes
- Validity criteria fulfilled:
- not applicable
- Conclusions:
- From the calculations it can be expected that the test material is readily biodegradable.
- Executive summary:
The given biodegradability of N-[2-(decanoylamino)ethyl]decanamide is calculated from BIOWIN 4.10 using the models BioWin3 and BioWin5. From the combined results it can be concluded that the test material is readily biodegradable. EPA recommends that EPI Suite is a screening-level tool and should not be used if acceptable measured values are available.
Referenceopen allclose all
Result Classification:
BioWin3: 5.00 -> hours, 4.00 -> days, 3.00 -> weeks, 2.00 -> months, 1.00 -> longer
BioWin5: A probability greater than or equal to 0.5 indicates readily degradable. A Probability less than 0.5 indicates not readily degradable.
Biowin3 | ||||
Type | Num | Biowin3 Fragment Description | Coeff | Value |
Frag | 2 | Linear C4 terminal chain [CCC-CH3] | 0.2983 | 0.5967 |
Frag | 2 | Aliphatic alcohol [-OH] | 0.1600 | 0.3199 |
Frag | 2 | Amide [-C(=O)-N or -C(=S)-N] | -0.0542 | -0.1084 |
MolWt | * | Molecular Weight Parameter | -1.3813 | |
Const | * | Equation Constant | 3.1992 | |
RESULT | Biowin3 (Survey Model - Ultimate Biodeg) | 2.6261 | ||
Biowin5 | ||||
Type | Num | Biowin5 Fragment Description | Coeff | Value |
Frag | 2 | Aliphatic alcohol [-OH] | 0.1611 | 0.3223 |
Frag | 2 | Amide [-C(=O)-N or -C(=S)-N] | 0.1266 | 0.2533 |
Frag | 2 | Methyl [-CH3] | 0.0004 | 0.0008 |
Frag | 32 | -CH2- [linear] | 0.0494 | 1.5813 |
Frag | 2 | -CH- [linear] | -0.0507 | -0.1013 |
MolWt | * | Molecular Weight Parameter | -1.8595 | |
Const | * | Equation Constant | 0.7121 | |
RESULT | Biowin5 (MITI Linear Biodeg Probability) | 0.9090 |
Result Classification:
BioWin3: 5.00 -> hours, 4.00 -> days, 3.00 -> weeks, 2.00 -> months, 1.00 -> longer
BioWin5: A probability greater than or equal to 0.5 indicates readily degradable. A Probability less than 0.5 indicates not readily degradable.
Biowin3 | ||||
Type | Num | Biowin3 Fragment Description | Coeff | Value |
Frag | 2 | Linear C4 terminal chain [CCC-CH3] | 0.2983 | 0.5967 |
Frag | 1 | Aliphatic alcohol [-OH] | 0.1600 | 0.1600 |
Frag | 2 | Amide [-C(=O)-N or -C(=S)-N] | -0.0542 | -0.1084 |
MolWt | * | Molecular Weight Parameter | -1.0979 | |
Const | * | Equation Constant | 3.1992 | |
RESULT | Biowin3 (Survey Model - Ultimate Biodeg) | 2.7495 | ||
Biowin5 | ||||
Type | Num | Biowin5 Fragment Description | Coeff | Value |
Frag | 1 | Aliphatic alcohol [-OH] | 0.1611 | 0.1611 |
Frag | 2 | Amide [-C(=O)-N or -C(=S)-N] | 0.1266 | 0.2533 |
Frag | 2 | Methyl [-CH3] | 0.0004 | 0.0008 |
Frag | 25 | -CH2- [linear] | 0.0494 | 1.2354 |
Frag | 1 | -CH- [linear] | -0.0507 | -0.0507 |
MolWt | * | Molecular Weight Parameter | -1.4781 | |
Const | * | Equation Constant | 0.7121 | |
RESULT | Biowin5 (MITI Linear Biodeg Probability) | 0.8340 |
Result Classification:
BioWin3: 5.00 -> hours, 4.00 -> days, 3.00 -> weeks, 2.00 -> months, 1.00 -> longer
BioWin5: A probability greater than or equal to 0.5 indicates readily degradable. A Probability less than 0.5 indicates not readily degradable.
Biowin3 | ||||
Type | Num | Biowin3 Fragment Description | Coeff | Value |
Frag | 2 | Linear C4 terminal chain [CCC-CH3] | 0.2983 | 0.5967 |
Frag | 2 | Amide [-C(=O)-N or -C(=S)-N] | -0.0542 | -0.1084 |
MolWt | * | Molecular Weight Parameter | -0.8146 | |
Const | * | Equation Constant | 3.1992 | |
RESULT | Biowin3 (Survey Model - Ultimate Biodeg) | 2.8729 | ||
Biowin5 | ||||
Type | Num | Biowin5 Fragment Description | Coeff | Value |
Frag | 2 | Amide [-C(=O)-N or -C(=S)-N] | 0.1266 | 0.2533 |
Frag | 2 | Methyl [-CH3] | 0.0004 | 0.0008 |
Frag | 18 | -CH2- [linear] | 0.0494 | 0.8895 |
MolWt | * | Molecular Weight Parameter | -1.0966 | |
Const | * | Equation Constant | 0.7121 | |
RESULT | Biowin5 (MITI Linear Biodeg Probability) | 0.7591 |
Description of key information
The calculations by EPI Suite BioWin predict that two of the three constituents are not readily biodegradable. Only N-[2-(decanoylamino)ethyl]decanamide (CAS 51139-08-3) is calculated as being readily biodegradable.
Key value for chemical safety assessment
Additional information
The given biodegradability is calculated from BIOWIN 4.10 using the models BioWin3 and BioWin5. From the combined results it can be concluded, that the substance is not readily biodegradable. Nevertheless, the EPA recommends that EPI Suite is a screening-level tool and should not be used if acceptable measured values are available.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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