2-Propenoic acid, methyl ester, reaction products with 2-ethyl-1-hexanamine and sodium hydroxide

Surface tension

Link to relevant study record(s)

Reference

Reference 1

Endpoint:

surface tension

Type of information:

experimental study

Adequacy of study:

key study

Study period:

March 09, 2018 - June 11, 2018

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

OECD Guideline 115 (Surface Tension of Aqueous Solutions)

Deviations:

no

Qualifier:

according to guideline

Guideline:

EU Method A.5 (Surface Tension)

Deviations:

no

GLP compliance:

yes (incl. QA statement)

Type of method:

OECD harmonised ring method

Specific details on test material used for the study:

- Composition of test material: Sodium-2-ethylhexyliminomonopropionate and Sodium-2-ethylhexyliminodipropionate
- Analytical purity: >=98%
- Purity test date: 13 December 2017
- Lot/batch No.: WI6K21X06-FD2
- Expiration date of the lot/batch: 05 December 2018
- Appearance: White paste
- Storage: At room temperature

Key result

Surface tension:

39.1 mN/m

Temp.:

20 °C

Conc.:

1 g/L

The results of the test on the determination of the surface tension of the test solution are given in the table below:

Measurement	Time passed after transfer test solution to test vessel [minutes]	Surface tension (mN/m)
		Individual	Mean	Mean multiplied by the calibration factor followed by correction according to Harkins-Jordan
1	15	41.5	41.2	39.1
2	16	41.0
3	17	41.2
4	18	41.2
5	19	41.0

Conclusions:

The OECD harmonized ring method was applied for the determination of the surface tension of the test item. The surface tension of a test solution at a concentration of 1 g/L in water and at 20°C was 39.1 mN/m. According to this, the test item is considered to be surface active.

Executive summary:

The surface tension of the test item was investigated in a GLP-compliant study performed in accordance with EC A.5 method and OECD Guideline No. 115, using the harmonized ring method. The surface tension of a test solution at a concentration of 1 g/L in water and at 20°C was 39.1 mN/m. According to this, the test item is considered to be surface active.

Reference 2

Endpoint:

surface tension

Type of information:

experimental study

Adequacy of study:

supporting study

Study period:

2011-12-02

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

other: Determination has been run accordingly to standardized method but without GLP compliance.

Qualifier:

according to guideline

Guideline:

OECD Guideline 115 (Surface Tension of Aqueous Solutions)

Deviations:

yes

Remarks:

pH was adjusted to 7.

GLP compliance:

no

Type of method:

OECD harmonised ring method

Surface tension:

52 mN/m

Temp.:

25 °C

Conc.:

1 g/L

The CMC is determined to 13.3 g/L at pH 7. Also, the surface tension at 1 g/L and pH 7 is determined to 52 mN/m.

Conclusions:

The CMC is determined to 13.3 g/L at pH 7. Also, the surface tension at 1 g/L and pH 7 is determined to 52 mN/m.

Executive summary:

The CMC is determined to 13.3 g/L at pH 7. Also, the surface tension at 1 g/L and pH 7 is determined to 52 mN/m.

Description of key information

The surface tension of 2-Propenoic acid, methyl ester, reaction products with 2-ethyl-1-hexanamine and sodium hydroxide (methanol free) was investigated in a GLP-compliant study performed in accordance with EC A.5 method and OECD Guideline No. 115, using the harmonized ring method. The surface tension of a test solution at a concentration of 1 g/L in water and at 20°C was 39.1 mN/m. According to this, the test item is considered to be surface active.

Key value for chemical safety assessment

Surface tension:

39.1

in mN/m at 20°C and concentration in mg/L:

1 000

Additional information

The surface tension of 2-Propenoic acid, methyl ester, reaction products with 2-ethyl-1-hexanamine and sodium hydroxide (methanol free) was determined in a GLP-compliant study performed in accordance with standard methods, without deviations. The study is considered as reliable (Klimisch 1) and was selected as key study for the endpoint.

The endpoint study summary for 2-Propenoic acid, methyl ester, reaction products with 2-ethyl-1-hexanamine and sodium hydroxide (methanol free) is linked to study record(s) on the substance itself but also to study record(s) on an analogue substance, a.k.a. Sodium 3-[(2-carboxyethyl)(2-ethylhexyl)amino]propanoate (CAS RN 94441-92-6 / EC 305-318-6). The latter is used as source substance to fill datagaps on 2-Propenoic acid, methyl ester, reaction products with 2-ethyl-1-hexanamine and sodium hydroxide (methanol free) for particular endpoints pertaining to environmental fate, aquatic toxicity and human health toxicity. Several physico-chemical data are thus reported for the source substance (e.g.physical state, melting point, vapour pressure, surface tension, water solubility and n-octanol/water partition coefficient – identified as “supporting studies”) to support the read-across approach (cf. read-across justification document attached in "13 Assessment reports").