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EC number: 947-965-2 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Adsorption / desorption
Administrative data
- Endpoint:
- adsorption / desorption: screening
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: Well documented guideline study without deviation
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 002
- Report date:
- 2002
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 106 (Adsorption - Desorption Using a Batch Equilibrium Method)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- batch equilibrium method
- Media:
- soil
Test material
- Reference substance name:
- (2-carboxyethyl)({2-[(2-carboxyethyl)(2-hydroxyethyl)amino]ethyl})azanium; [({2-[(2-carboxyethyl)(2-hydroxyethyl)amino]ethyl}carbamoyl)methyl](dodecyl)dimethylazanium; ethanol
- IUPAC Name:
- (2-carboxyethyl)({2-[(2-carboxyethyl)(2-hydroxyethyl)amino]ethyl})azanium; [({2-[(2-carboxyethyl)(2-hydroxyethyl)amino]ethyl}carbamoyl)methyl](dodecyl)dimethylazanium; ethanol
Constituent 1
- Radiolabelling:
- no
Study design
- Test temperature:
- 20 °C (+/-) 2 °C
Batch equilibrium or other method
- Analytical monitoring:
- yes
- Details on sampling:
- - Concentrations: 21 mg/l
- Sampling times adsorption (hours): 3:45, 6:15, 23:45, 47
-Sampling time desorption: 4:30 h
Duration of adsorption equilibrationopen allclose all
- Sample No.:
- #1
- Duration:
- 47 h
- Initial conc. measured:
- 21.621 other: µg/mL
- pH:
- 5.06
- Temp.:
- 20 °C
- Sample No.:
- #2
- Duration:
- 47 h
- Initial conc. measured:
- 21.212 other: µg/mL
- pH:
- 7.1
- Temp.:
- 20 °C
- Sample No.:
- #3
- Duration:
- 47 h
- Initial conc. measured:
- 21.11 other: µg/mL
- pH:
- 7.13
- Temp.:
- 20 °C
- Sample No.:
- #4
- Duration:
- 47 h
- Initial conc. measured:
- 21.459 other: µg/mL
- pH:
- 5.18
- Temp.:
- 20 °C
- Sample No.:
- #5
- Duration:
- 47 h
- Initial conc. measured:
- 21.107 other: µg/mL
- pH:
- 7.63
- Temp.:
- 20 °C
Duration of desorption equilibrationopen allclose all
- Sample no.:
- #1
- Duration:
- 4 h
- Conc. of adsorbed test mat.:
- 0.148 other: µg/mL
- pH:
- 4.9
- Temp.:
- 20 °C
- Sample no.:
- #2
- Duration:
- 4 h
- Conc. of adsorbed test mat.:
- 0.304 other: µg/mL
- pH:
- 6.94
- Temp.:
- 20 °C
- Sample no.:
- #3
- Duration:
- 4 h
- Conc. of adsorbed test mat.:
- 0.269 other: µg/mL
- pH:
- 6.37
- Temp.:
- 20 °C
- Sample no.:
- #4
- Duration:
- 4 h
- Conc. of adsorbed test mat.:
- 0.299 other: µg/mL
- pH:
- 5.06
- Temp.:
- 20 °C
- Sample no.:
- #5
- Duration:
- 4 h
- Conc. of adsorbed test mat.:
- 0.228 other: µg/mL
- pH:
- 6.94
- Temp.:
- 20 °C
Results and discussion
Adsorption coefficientopen allclose all
- Type:
- Koc
- Value:
- 7 353
- Temp.:
- 20 °C
- Remarks on result:
- other: Soil: Speyer 2.1
- Type:
- Koc
- Value:
- 2 454
- Temp.:
- 20 °C
- Remarks on result:
- other: Soil: Cranfield 115
- Type:
- Koc
- Value:
- 1 370
- Temp.:
- 20
- Remarks on result:
- other: Soil: Cranfield 164
- Type:
- Koc
- Value:
- 3 755
- Temp.:
- 20 °C
- Remarks on result:
- other: Soil: Cranfield 243
- Type:
- Koc
- Value:
- 1 778
- Temp.:
- 20 °C
- Remarks on result:
- other: Soil: Speyer 6 S
- Type:
- Kd
- Value:
- 41.4
- Temp.:
- 20 °C
- Remarks on result:
- other: Soil: Speyer 2.1
- Type:
- Kd
- Value:
- 41.3
- Temp.:
- 20 °C
- Remarks on result:
- other: Soil: Cranfield 115
- Type:
- Kd
- Value:
- 41.3
- Temp.:
- 20 °C
- Remarks on result:
- other: Soil: Cranfield 164
- Type:
- Kd
- Value:
- 41.4
- Temp.:
- 20 °C
- Remarks on result:
- other: Soil: Cranfield 243
- Type:
- Kd
- Value:
- 41.3
- Temp.:
- 20 °C
- Remarks on result:
- other: Soil: Speyer 6 S
Partition coefficientsopen allclose all
- Phase system:
- other: Kom (organic matter normalised adsorption coefficient)
- Type:
- other: Kom (organic matter normalised adsorption coefficient)
- Value:
- 4 265 L/kg
- Remarks on result:
- other: Soil: Speyer 2.1
- Phase system:
- other: organic matter normalised adsorption coefficient
- Type:
- other: organic matter normalised adsorption coefficient
- Value:
- 1 423 L/kg
- Remarks on result:
- other: Soil: Cranfield 115
- Phase system:
- other: organic matter normalised adsorption coefficient
- Type:
- other: organic matter normalised adsorption coefficient
- Value:
- 795 L/kg
- Remarks on result:
- other: Soil: Cranfield 164
- Phase system:
- other: organic matter normalised adsorption coefficient
- Type:
- other: organic matter normalised adsorption coefficient
- Value:
- 2 178 L/kg
- Remarks on result:
- other: Soil: Cranfield 243
- Phase system:
- other: organic matter normalised adsorption coefficient
- Type:
- other: organic matter normalised adsorption coefficient
- Value:
- 1 031 L/kg
- Remarks on result:
- other: Soil: Speyer S 6
Results: Batch equilibrium or other method
- Transformation products:
- no
- Details on results (Batch equilibrium method):
- MAIN TEST: PERFORMANCE
- Test material stability during adsorption/desorption phase: substance is stable
- Experimental conditions maintained throughout the study: Yes
Any other information on results incl. tables
Measured test substance concentrations in adsorption/desorption samples were all <= 1 mg/L for Speyer 2.1 soil and all < 1 mg/L for the other four soils. This would correspond to at least 95.3 % adsorption of test substance on all test soils. However, in view of the fact that high (> 90 %) and low (< 10%) degrees of adsorption cannot be accurately determined for unlabelled test substances and in view of the results for the calibration curves, these results were deemed uncertain. Notwithstanding, from the analyses it became clear that the adsorption/desorption samples all contained <= 1 mg test substance/L. The concentration of 1 mg test substance/L, corresponding to 95 % adsorption in all test soils, was therefore taken as the maximum value for the test substance concentration in all samples and used in the calculations of Kd, KOC, K, and Kdes. The results for the adsorption and desorption coefficients are therefore to be regarded as minimum values.
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Executive summary:
The adsorption behaviour of the substance on five soils, encompassing a range of pH values, soil types (i.e. % clay, silt and sand) and % organic matter was investigated according to OECD guideline 106. The test soils were Speyer 2.1 [0.97% organic matter (OM), sand], Speyer 6 S [4.0 % OM, clay], Cranfield 115 [2.9 % OM, clay loam], Cranfield 164 [5.2 % OM, silt loam] and Cranfield 243 [1.9% OM, sandy loam]. Adsorption was studied using the batch equilibrium method. Adsorption and desorption kinetics were determined at an initial test substance concentration of approximately 21 mg/L and at 20 °C (+/-) 2 °C in the dark. Adsorption equilibrium was reached very quickly within 4 hours. There was no indication that the substance adsorbed to the container walls or was unstable during the adsorption test. The analytical method available for the substance had to be modified for measurement of adsorption/desorption samples, but nevertheless remained unsatisfactory for accurately quantifying the substance in these samples. For the calculation of the adsorption coefficients, a maximum equilibrium concentration of test substance of 1 mg/L could be taken. Mean Kom ads (organic matter normalised adsorption coefficient) values were 4265 cm3/g (Speyer 2.1) 1423 cm3/g (Cranfield 115), 795 cm3/g (Cranfield 164), 2178 cm3/g (Cranfield 243) and 1031 cm3/g (Speyer 6 S). The substance can therefore be considered to be immobile in all five soils investigated according to the classification scheme by Mensink.
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