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Diss Factsheets
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EC number: 278-115-2 | CAS number: 75199-13-2
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- key study
- Study period:
- 15 July to 15 August, 2002
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- guideline study
- Justification for type of information:
- The justification of the read across is reported and detailed into the IUCLID section 13.
- Reason / purpose for cross-reference:
- read-across source
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 F (Ready Biodegradability: Manometric Respirometry Test)
- Version / remarks:
- 1992
- GLP compliance:
- yes (incl. QA statement)
- Duration of test (contact time):
- 28 d
- Initial conc.:
- 100 mg/L
- Based on:
- test mat.
- Initial conc.:
- 175 - 226 mg/L
- Based on:
- ThOD
- Remarks:
- Nh4/NO3, i.e. without / with nitrification
- Parameter followed for biodegradation estimation:
- O2 consumption
- Parameter:
- % degradation (O2 consumption)
- Remarks:
- ThOD NH4
- Value:
- 0 - 6
- Sampling time:
- 28 d
- Parameter:
- % degradation (O2 consumption)
- Remarks:
- ThODNO3
- Value:
- 0 - 5
- Sampling time:
- 28 d
- Interpretation of results:
- not readily biodegradable
- Conclusions:
- The substance was found to be not biodegradable under the test conditions within 28 days.
- Executive summary:
The test item was investigated for its ready biodegradability in a manometric respirometry test over 28 days based on EU Commission Directive 92/69/EEC, C.4-D (1992) and OECD guideline 301F (1992).
The percent biodegradation of the test item was calculated based on the theoretical oxygen demand of 1.75 mg O2/mg test item without nitrification (ThODNH4) and 2.26 mg O2/mg test item with nitrification (ThODNO3).
The biochemical oxygen demand (BOD) of the test item in the test media was within the range of the inoculum controls.
Consequently, the substance was found to be not biodegradable under the test conditions within 28 days.
In the toxicity control, containing both test item and the reference item sodium benzoate, no inhibitory effect on the biodegradation of the reference item was determined. Thus, the test item had no inhibitory effect on the activity of activated sludge microorganisms.
In the procedure controls, the reference item sodium benzoate was biodegraded by an averege of 86 % on exposure day 14, and reached an average biodegradation rate of 90 % by the end of the test (day 28), thus confìrming suitability of the activated sludge.
Reference
Description of key information
Not readily biodegradable
Key value for chemical safety assessment
- Type of water:
- freshwater
Additional information
The ready biodegradability potential of test substance was assessed relying on a data on structural analogue, i.e. Similar Substance 01. Details on the read across are available in section 13.
Similar Substance 01 was tested according to OECD guideline 301F and was found to be non ready biodegradable.
In general, mono-azo dyes are not expected to be ready biodegradable due to the chemical structure and the technical function. Commonly, dyes undergo a primary transformation, i.e. discolouration, due to interruption of the conjugation. However, a degradation process involves more steps and takes more time, thus such dyes are not considered readily biodegradable.
Disperse Yellow 231 was found to be inherently biodegradable in a MITI (II) test; 100 % biodegradation was seen after 14 days of exposure under aerobic conditions. However, due to the lack of details on test conditions and observations, the reliability of such data could not be ascertained.
Moreover, as reported in the Guidance on application of CLP criteria (v. 5.0 - July 2017), substances that are degraded more than 70 % in tests for inherent biodegradability (OECD guidelines 302) have the potential for ultimate biodegradation. However, because of the optimised conditions in these tests, the rapid biodegradability of inherently biodegradable substances in the environment cannot be assumed. The optimised conditions in inherent biodegradability tests stimulate adaptation of the micro-organisms thus increasing the biodegradation potential, compared to natural environments. Therefore, positive results in general should not be interpreted as evidence for rapid degradation in the environment.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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