Registration Dossier
Registration Dossier
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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 200-996-9 | CAS number: 76-99-3
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Administrative data
First-aid measures
Contact with skin : flush with plenty of water, remove contaminated cothing, immediatelly call doctor
Contact with eyes: flush with plenty of water for at least 15 minutes, immediatelly call doctor
Ingestion : do not induce vomiting, immediatelly call doctor
Fire-fighting measures
not to be used: strong water jet
Equipment for self-protection: self-contained breathing equipment ,protective clothing rubber gloves.
Accidental release measures
Environmental precautions: Avoid accumulation of product near water flows and watersources.
Methods and material for containment and cleaning up: Pick up mechanically and put residual in suitable labelled containers and send it as dangerous waste for disposal.
Handling and storage
Ensure adequate ventilation on workplace. Avoid dust formation. Avoid prolonged contact with skin and eyes. Avoid breathing of dust or vapours from technological process. Use protective suit and gloves. Take off contaminated clothing and wash before reuse. Workers have obligation to fill the professional competence for work with toxical chemicals (Slovakia).
Storage :
Store in closed containers in dry, dark room. Product is sensitive to light an moisture!
Recommended storrage temperature: 15°C to 25°C
Recommended packaging material: glass, PE, PP
Transport information
Land transport (UN RTDG/ADR/RID)
- UN number:
- 1544
Shipping information
- Proper shipping name and description:
- ALKALOIDY, PEVNÉ, I. N. alebo ALKALOIDOVÉ SOLI, PEVNÉ, I. N.
- Chemical name:
- metadon
- Language:
- Slovak
- Labels:
- 6.1
SpecialProvisionsopen allclose all
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Marine transport (UN RTDG/IMDG)
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Exposure controls / personal protection
Hand protection:
protective gloves, material: Nitril rubber, thickness: 0,11mm, penetration time: > 480min.
protective clothing and shoes, antistatic
Eye protection: protective glasses (EN 166)
Body protection: protective clothing
Stability and reactivity
Conditions to avoid: hign tempereture, light, moisture
Incompatible materials: strong oxidisers
Disposal considerations
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.