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Diss Factsheets
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EC number: 915-610-0 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Water solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 19 to 23 June 2017
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 105 (Water Solubility)
- Version / remarks:
- 2014
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.6 (Water Solubility)
- GLP compliance:
- yes (incl. QA statement)
- Remarks:
- Staatliches Gewerbeaufsichtsamt Hildesheim, Hildesheim, Germany
- Type of method:
- flask method
- Key result
- Water solubility:
- 211 mg/L
- Conc. based on:
- test mat.
- Temp.:
- 20 °C
- pH:
- 7.2
- Conclusions:
- A water solubility value of 211 mg/L (at 20 °C, pH = 7.2) was determined for the test substance according to OECD 105.
- Executive summary:
The water solubility of the test item for the temperatures 20 °C was determined according to OECD 105 and GLP using a flask method with pre-incubation at 30°C. The concentrations were verified via HPLC-DAD method. The test item was quantified based on the sum of three signals.
Reference
Check of the temperature
Temperature at Pre-Incubation (30 °C) and Thermostatisation Phase (20 °C) (measured hourly)
Intended temperature [°C] |
Measured temperature. [°C] |
||
|
min. |
max. |
Mean value ± SD |
30.0 ±0.5 |
29.78 |
30.10 |
30.04 ± 0.05 |
20.0 ± 0.5 |
19.93 |
20.17 |
19.96 ± 0.05 |
Check of the pH-Value
The pH-values were determined with the remaining test item mixtures in the original test vessels, which were kept constant at 20 ± 0.5 °C.
Test temperature [°C] |
Pre-incubation time [h] |
Replicate |
Measured pH |
Mean value |
20 |
24 |
1 |
7.060 |
7.2 |
2 |
7.219 |
|||
48 |
1 |
7.310 |
||
2 |
7.324 |
|||
72 |
1 |
7.304 |
||
2 |
7.250 |
|||
Control |
7.217 |
- |
Water Solubility Results
No significant signals were obtained for the control sample.
The water solubility results at 20 °C for the test item are reported in the following table.
Preincubation time |
Replicate No. |
Concentration (1) [mg/L] |
Mean [mg/L] |
24 h |
1 |
207 |
214 |
2 |
221 |
||
48 h |
1 |
205 |
205 |
2 |
206 |
||
72 h |
1 |
216 |
213 |
2 |
211 |
||
Mean (24 - 72 h) |
|
|
211 |
Deviation [%] (24 - 72 h) |
|
|
4.1 |
(1) Mean value of two injections, dilution factor of 10 and exact weight of the standard taken into account
Conclusion
The solubility of the test item was determined at 20 ± 0.5 °C to be 211 mg/L (pH 7.2).
Description of key information
Water solubility: 211 mg/L at 20 °C, pH = 7.2 (OECD 105, flask method)
Key value for chemical safety assessment
- Water solubility:
- 211 mg/L
- at the temperature of:
- 20 °C
Additional information
According to OECD 105 and GLP, the water solubility of the test item for the temperatures 20 °C was determined using a flask method with pre-incubation at 30°C. The concentrations were verified via HPLC-DAD method. The test item was quantified based on the sum of three signals.
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